Department of Anesthesiology, Hospital de Clínicas "José de San Martín", Buenos Aires, Argentina.
J Anesth. 2022 Dec;36(6):770-781. doi: 10.1007/s00540-022-03105-z. Epub 2022 Sep 22.
If we define the human body by the mass of the elements that compose it, we could say that we are oxygen and other elements. Oxygen, in addition to being fundamental in our composition, is an element that we constantly need to support cellular respiration and, therefore, life. Interestingly, despite its importance, humans have not developed mechanisms that allow us to store it and, therefore, we are unable to sustain life if we are deprived of ventilation, even for brief periods. Accordingly, the ability to induce the cessation of ventilation in a patient must be accompanied by different technical and non-technical skills that allow the patient's safety to be maintained in this highly vulnerable state. Through the use of basic mathematical tools and comparative physiology, we hereby propose to review the physiological foundations of preoxygenation to understand the reasons behind the clinical recommendations in this field.
如果我们根据组成人体的元素的质量来定义人体，那么我们可以说人体是由氧气和其他元素组成的。氧气不仅是我们身体构成的基础，还是维持细胞呼吸和生命所必需的元素。有趣的是，尽管氧气非常重要，但人类并没有发展出能够储存氧气的机制，如果我们被剥夺了通气，即使是短暂的时间，我们也无法维持生命。因此，在患者身上诱导停止通气的能力必须伴随着不同的技术和非技术技能，以确保患者在这种高度脆弱的状态下保持安全。通过使用基本的数学工具和比较生理学，我们在此提出回顾预充氧的生理学基础，以了解该领域临床建议背后的原因。
