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紫锥菊((L.) Moench)为基础的膳食补充剂中霉菌及其次级代谢产物的存在。

The Presence of Molds and Their Secondary Metabolites in Purple Coneflower-Based Dietary Supplements ( (L.) Moench).

机构信息

Department of Physiology and Toxicology, Faculty of Biological Sciences, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland.

出版信息

Toxins (Basel). 2022 Sep 1;14(9):607. doi: 10.3390/toxins14090607.

DOI:10.3390/toxins14090607
PMID:36136545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9502472/
Abstract

Purple coneflower ( (L.) Moench) is a plant in the family , mainly grown in North America. has been used in conventional medicine. The plant has immuno-stimulating and antibacterial properties, but neither mold contamination nor a mycotoxin presence have been evaluated. Our goal is to determine the degree to which molds and mycotoxins contaminate dietary supplements based on purple coneflower distributed on the Polish market. We analyzed 21 samples divided into four groups: sachets ( = 5), dry raw material ( = 3), capsules ( = 9), and tablets ( = 4). The mycological analysis of dietary supplements shows that the average number of molds is 1012 cfu/g, and the most common molds are spp., spp. and spp. The mycotoxins most common in the samples are ZEN (18/21), DON (5/21) and T-2 toxin (3/21).

摘要

紫锥菊(Echinacea purpurea (L.) Moench)是菊科植物,主要生长在北美。在传统医学中已被使用。该植物具有免疫刺激和抗菌特性,但尚未评估霉菌污染和霉菌毒素的存在。我们的目标是确定基于分布在波兰市场上的紫锥菊的膳食补充剂中霉菌和霉菌毒素的污染程度。我们分析了 21 个样本,分为四组:小袋(=5)、干原料(=3)、胶囊(=9)和片剂(=4)。膳食补充剂的真菌分析表明,霉菌的平均数量为 1012 cfu/g,最常见的霉菌是 spp.、 spp. 和 spp.。在样品中最常见的霉菌毒素是 ZEN(18/21)、DON(5/21)和 T-2 毒素(3/21)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/927a/9502472/6e750b13c0fb/toxins-14-00607-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/927a/9502472/33c6debf1032/toxins-14-00607-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/927a/9502472/6e750b13c0fb/toxins-14-00607-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/927a/9502472/33c6debf1032/toxins-14-00607-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/927a/9502472/6e750b13c0fb/toxins-14-00607-g002.jpg

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本文引用的文献

1
Mycotoxins occurrence in medicinal herbs dietary supplements and exposure assessment.药用植物膳食补充剂中霉菌毒素的存在情况及暴露评估。
J Food Sci Technol. 2022 Jul;59(7):2830-2841. doi: 10.1007/s13197-021-05306-y. Epub 2021 Nov 10.
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Dietary Supplements Based on Red Yeast Rice-A Source of Citrinin?基于红曲米的膳食补充剂——桔霉素的来源?
Toxins (Basel). 2021 Jul 17;13(7):497. doi: 10.3390/toxins13070497.
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Drinking Green Tea: Despite the Risks Due to Mycotoxins, Is It Possible to Increase the Associated Health Benefits?
饮用绿茶:尽管存在真菌毒素风险,但增加相关健康益处是否可行?
Toxins (Basel). 2021 Feb 5;13(2):119. doi: 10.3390/toxins13020119.
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Ochratoxin A and citrinin in green coffee and dietary supplements with green coffee extract.生咖啡及含生咖啡提取物的膳食补充剂中的赭曲霉毒素A和桔霉素。
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In vitro virucidal activity of Echinaforce®, an Echinacea purpurea preparation, against coronaviruses, including common cold coronavirus 229E and SARS-CoV-2.紫锥菊制剂 Echinaforce®抗冠状病毒(包括普通感冒冠状病毒 229E 和 SARS-CoV-2)的体外病毒杀灭活性。
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Poor chemical and microbiological quality of the commercial milk thistle-based dietary supplements may account for their reported unsatisfactory and non-reproducible clinical outcomes.商业奶蓟草为基础的膳食补充剂的较差的化学和微生物质量可能是其报道的不满意和不可重现的临床结果的原因。
Sci Rep. 2019 Jul 31;9(1):11118. doi: 10.1038/s41598-019-47250-0.
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Optimized QuEChERS Method Combined with UHPLC-MS/MS for the Simultaneous Determination of 15 Mycotoxins in Liquorice.优化的QuEChERS方法结合超高效液相色谱-串联质谱法同时测定甘草中的15种霉菌毒素
J AOAC Int. 2018 May 1;101(3):633-642. doi: 10.5740/jaoacint.17-0365. Epub 2017 Oct 26.
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