Liao Bing, Xu Dali, Tan Yingyao, Chen Xiong, Cai Shu
School of Nursing, Guangdong Pharmaceutical University, Haizhu District, Guangzhou, China; Department of Nursing, Central People's Hospital of Zhanjiang, Chikan District, Zhanjiang, China.
Department of Psychiatry and Neuroimaging Centre, Wenzhou Seventh People's Hospital, Wenzhou, Zhejiang, China.
J Psychosom Res. 2022 Nov;162:111040. doi: 10.1016/j.jpsychores.2022.111040. Epub 2022 Sep 14.
Mental distress has a high global prevalence and is associated with poor health outcomes. This study aimed to estimate the relationship between mental distress and the risk of 10 chronic diseases using data from the Behavioral Risk Factor Surveillance System (BRFSS).
Cross-sectional data from the 2013, 2014, 2015, 2016 and 2017 BRFSS were analyzed. The association between mental distress based on the number of days of poor mental health and the risk of 10 chronic diseases, namely obesity, diabetes, asthma, chronic obstructive pulmonary disease (COPD), arthritis, kidney disease, coronary heart disease (CHD), stroke, skin cancer, and other cancers, were assessed by logistic regression models to calculate odds ratios and 95% confidence intervals. Subgroup analyses stratified by age and sex were also conducted.
Positive associations between mental distress and chronic diseases were observed. We also found a dose-response gradient between mental distress levels and the risk of all chronic diseases except skin cancer. In respondents aged 18-44 years reporting ≥23 days/month of mental distress, there has the largest odds ratio between mental distress levels and each chronic disease. Moreover, mental distress was associated with higher risks of obesity and arthritis in women relative to men.
Mental distress was positively associated with chronic diseases. Age and sex are crucial in this relationship. Further studies with longitudinal data are needed to clarify the direction of this association.
精神困扰在全球具有很高的患病率，且与不良健康结局相关。本研究旨在利用行为危险因素监测系统（BRFSS）的数据评估精神困扰与10种慢性病风险之间的关系。
分析了2013年、2014年、2015年、2016年和2017年BRFSS的横断面数据。基于心理健康状况不佳天数的精神困扰与10种慢性病（即肥胖症、糖尿病、哮喘、慢性阻塞性肺疾病（COPD）、关节炎、肾病、冠心病（CHD）、中风、皮肤癌和其他癌症）风险之间的关联，通过逻辑回归模型进行评估，以计算比值比和95%置信区间。还进行了按年龄和性别分层的亚组分析。
观察到精神困扰与慢性病之间存在正相关。我们还发现，除皮肤癌外，精神困扰水平与所有慢性病风险之间存在剂量反应梯度。在报告每月有≥23天精神困扰的18 - 44岁受访者中，精神困扰水平与每种慢性病之间的比值比最大。此外，相对于男性，女性的精神困扰与肥胖症和关节炎的较高风险相关。
精神困扰与慢性病呈正相关。年龄和性别在这种关系中至关重要。需要进一步开展纵向数据研究以阐明这种关联的方向。
