Pingree T F, Davis R K, Reichman O, Derrick L
Laryngoscope. 1987 Aug;97(8 Pt 1):901-4.
A computer search of cancer patients enrolled in the Rocky Mountain Cancer Data System between 1973 to 1983 revealed 1,362 patients with hypopharyngeal cancer, 1,208 of whom could be staged by the American Joint Committee on cancer staging criteria. Stage I and II patients comprised 17.5% while 71% were either stages III or IV. The distant metastatic rate in advanced stage patients was 24%. Survivals for all treated patients were 65% at 1 year, 33.5% at 3 years, and 25% at 5 years. Three-year survivals were 54.5% for the surgery only group, 41.6% for the combined therapy group, and 17.7% for the irradiation only group. Five-year survivals for the surgery only group were 39.8%, combined therapy, 31.8%, and irradiation only 11.5%. These figures are actuarially corrected. Twenty-two percent of combined therapy patients had preoperative irradiation versus 78% who had postoperative irradiation. There was no statistically significant difference seen between these two groups.
对1973年至1983年间登记在落基山癌症数据系统中的癌症患者进行的计算机检索显示,有1362例下咽癌患者,其中1208例可根据美国癌症联合委员会的分期标准进行分期。I期和II期患者占17.5%,而III期或IV期患者占71%。晚期患者的远处转移率为24%。所有接受治疗患者的1年生存率为65%,3年生存率为33.5%,5年生存率为25%。单纯手术组的3年生存率为54.5%,联合治疗组为41.6%,单纯放疗组为17.7%。单纯手术组的5年生存率为39.8%,联合治疗组为31.8%,单纯放疗组为11.5%。这些数字经过了精算校正。22%的联合治疗患者接受了术前放疗,78%接受了术后放疗。这两组之间未观察到统计学上的显著差异。