Kasprzycka Wiktoria, Naurecka Magdalena Ligia, Sierakowski Bartosz Michał, Putko Paulina, Mierczyk Zygmunt, Chabik Grzegorz, Dec Stanisław, Gaździński Stefan, Rola Rafał
Biomedical Engineering Centre, Institute of Optoelectronics, Military University of Technology, 00-908 Warsaw, Poland.
Department of Neurology, Military Institute of Aviation Medicine, 01-755 Warsaw, Poland.
Brain Sci. 2022 Sep 14;12(9):1241. doi: 10.3390/brainsci12091241.
Transcranial magnetic stimulation (TMS) is a method of noninvasive and painless stimulation of the nervous system, which is based on Faraday's law of electromagnetic induction. Over the past twenty years, the TMS technique has been deployed as a tool for the diagnosis and therapy of neurodegenerative diseases, as well as in the treatment of mental disorders (e.g., depression).
We tested the inhibitory effects of repetitive TMS (rTMS) on reaction times to militarily relevant visual stimuli amidst distractors and on accompanying blood oxygenation level dependent (BOLD) signal functional magnetic resonance imaging (fMRI) in 20 healthy people. rTMS was applied over the visual cortices, V1, on both hemispheres with the inhibitory theta burst paradigm with the intensity of 70% of the active motor threshold fMRI in 20 healthy people.
Analysis of the reaction time to visual stimuli after using TMS to the V1 visual cortex revealed an increase in the number of incorrect recognitions, and the reaction time was from 843 to 910 ms. In the subgroup of participants ( = 15), after the stimulation, there were significant reductions of BOLD signal in blood flow within V1 cortices.
The studies of reaction times after the rTMS revealed the inhibitory effect of rTMS on the reaction times and recognition performance of significant (military) objects in the visual field.
经颅磁刺激（TMS）是一种基于法拉第电磁感应定律的无创、无痛的神经系统刺激方法。在过去二十年中，TMS技术已被用作神经退行性疾病的诊断和治疗工具，以及用于治疗精神障碍（如抑郁症）。
我们测试了重复经颅磁刺激（rTMS）对20名健康人在干扰物存在的情况下对军事相关视觉刺激的反应时间以及伴随的血氧水平依赖（BOLD）信号功能磁共振成像（fMRI）的抑制作用。在20名健康人的两个半球的视觉皮层V1上应用rTMS，采用抑制性theta爆发模式，强度为主动运动阈值fMRI的70%。
对V1视觉皮层进行TMS后对视觉刺激的反应时间分析显示，错误识别数量增加，反应时间从843毫秒增加到910毫秒。在参与者亚组（n = 15）中，刺激后V1皮层内血流的BOLD信号显著降低。
rTMS后反应时间的研究揭示了rTMS对视野中重要（军事）物体的反应时间和识别性能的抑制作用。
