Shandong Provincial Key Laboratory of Detection Technology for Tumor Markers, Linyi University, Linyi 276005, China.
College of Chemistry and Bioengineering, Hunan University of Science and Engineering, Yongzhou 425100, China.
Biosensors (Basel). 2022 Sep 15;12(9):758. doi: 10.3390/bios12090758.
The development of biosensing platforms has been impressively accelerated by advancements in liquid crystal (LC) technology. High response rate, easy operation, and good stability of the LC droplet-based biosensors are all benefits of the long-range order of LC molecules. Bioprobes emerged when LC droplets were combined with biotechnology, and these bioprobes are used extensively for disease diagnosis, food safety, and environmental monitoring. The LC droplet biosensors have high sensitivity and excellent selectivity, making them an attractive tool for the label-free, economical, and real-time detection of different targets. Portable devices work well as the accessory kits for LC droplet-based biosensors to make them easier to use by anyone for on-site monitoring of targets. Herein, we offer a review of the latest developments in the design of LC droplet-based biosensors for qualitative target monitoring and quantitative target analysis.
液晶（LC）技术的进步令人印象深刻地加速了生物传感平台的发展。基于 LC 液滴的生物传感器具有高响应速度、易于操作和良好的稳定性，这都得益于 LC 分子的长程有序性。当 LC 液滴与生物技术结合时，就出现了生物探针，这些生物探针被广泛用于疾病诊断、食品安全和环境监测。LC 液滴生物传感器具有高灵敏度和出色的选择性，使其成为用于无标记、经济和实时检测不同目标的有吸引力的工具。便携式设备作为 LC 液滴生物传感器的附件套件，可以使任何人都更容易在现场监测目标。本文综述了用于定性目标监测和定量目标分析的 LC 液滴生物传感器设计的最新进展。
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