Dental School, Vita-Salute San Raffaele University, 20132 Milan, Italy.
Department of Dentistry, IRCCS San Raffaele Hospital, 20132 Milan, Italy.
Int J Environ Res Public Health. 2022 Sep 17;19(18):11735. doi: 10.3390/ijerph191811735.
The aim of this retrospective clinical study was to evaluate and compare implant survival, marginal bone loss, and clinical and prosthetic complications in healthy patients and patients with type I diabetes undergoing full arch implant-prosthetic rehabilitation. A total of 47 patients needing total fixed rehabilitation of one or both arches were enrolled for this study. Based on the absence of any systemic diseases (Group A) or the presence of type I diabetes (Group B), the sample was divided into two groups. According to the grade of bone atrophy in the posterior region, patients received full arch rehabilitation (of one or both jaws) with 6 axial implants or, if the residual posterior bone height was insufficient, All-on-Four rehabilitation and a total 236 dental implants were placed. Follow-up visits were performed 1 week after surgery, at 3 and 6 months and then once a year for the next 10 years. No statistically significant differences between groups were recorded about implant survival rates, marginal bone loss, or clinical and prosthetic complications. However, concerning complications, post-surgical bleeding and wound infection were recorded in Group A more than in Group B. In cases of compensated diabetes compensation, implant placement could be considered a safe procedure.
本回顾性临床研究旨在评估和比较健康患者和 I 型糖尿病患者接受全颌种植体-修复体康复治疗后的种植体存活率、边缘骨丧失、临床和修复体并发症。本研究共纳入 47 名需要单颌或双颌全固定修复的患者。根据是否存在任何系统性疾病(A 组)或是否存在 I 型糖尿病(B 组),将样本分为两组。根据后牙区骨萎缩程度,患者接受 6 个轴向种植体的全颌修复(单颌或双颌),或如果后牙剩余骨高度不足,则接受 All-on-Four 修复,并总共植入 236 颗牙种植体。术后 1 周、3 个月和 6 个月以及接下来的 10 年内每年进行随访。两组之间的种植体存活率、边缘骨丧失或临床和修复体并发症无统计学差异。然而,关于并发症,A 组的术后出血和伤口感染发生率高于 B 组。在糖尿病得到代偿的情况下,种植体植入可被视为一种安全的治疗方法。