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[老年颅内动脉瘤患者的治疗问题]

[Therapeutic problems in aged patients with intracranial aneurysms].

作者信息

Oka K, Kuromatsu C, Takaki T, Maeyama R, Fukui M, Kitamura K

出版信息

No Shinkei Geka. 1987 Apr;15(4):375-9.

PMID:3614529
Abstract

In a series of 404 patients with intracranial saccular aneurysm, 61 were over 65 years of age. Ten of these aged patients had no surgery. The operative mortality in the aged patients was 11.8%. While the mortality rate in patients below 65 years was 6.1%. The main complication following intracranial surgery for aneurysm consisted of cerebral infarction due to vasospasm, hydrocephalus, intracranial hematoma and general complications. The incidence of angiographical vasospasm was 22.6% in the aged patients and 43.6% in the young patients. There is no significant difference in vasospasm following subarachnoid hemorrhage between the aged and young patients. Cerebral infarction occurred in 27.5% of the aged patients and in 24.6% of the young patients. Severe cerebral infarction was found in 92.9% of the aged patients and in 58% of the young patients. Vasospasm resulted in broad cerebral infarction significantly more frequently in the aged patients, but cerebral infarction proved was non-fatal in the aged patients. Ventricular dilatation detected by CT was found in 33.3% of the aged patients and in 24.2% of the young patients. In patients with ventricular dilatation, 82.4% of the aged patients needed ventriculo-peritoneal shunt (V-P shunt). On the other hand, 39.3% of the young patients had V-P shunt. There was no significant difference for ventricular dilatation detected by CT between the aged and young patients. The aged patients depended on V-P shunt significantly more than did the young patients.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在一组404例颅内囊状动脉瘤患者中,61例年龄超过65岁。这些老年患者中有10例未接受手术。老年患者的手术死亡率为11.8%。而65岁以下患者的死亡率为6.1%。颅内动脉瘤手术后的主要并发症包括血管痉挛导致的脑梗死、脑积水、颅内血肿和全身并发症。老年患者血管造影显示血管痉挛的发生率为22.6%,年轻患者为43.6%。老年和年轻患者蛛网膜下腔出血后血管痉挛的发生率无显著差异。老年患者脑梗死发生率为27.5%,年轻患者为24.6%。重度脑梗死在老年患者中占92.9%,在年轻患者中占58%。血管痉挛导致老年患者广泛脑梗死的频率明显更高,但老年患者的脑梗死并非致命。CT检测到脑室扩张在老年患者中占33.3%,在年轻患者中占24.2%。在脑室扩张的患者中,82.4%的老年患者需要行脑室-腹腔分流术(V-P分流术)。另一方面,39.3%的年轻患者行V-P分流术。CT检测到的脑室扩张在老年和年轻患者之间无显著差异。老年患者对V-P分流术的依赖明显高于年轻患者。(摘要截短至250字)

相似文献

1
[Therapeutic problems in aged patients with intracranial aneurysms].[老年颅内动脉瘤患者的治疗问题]
No Shinkei Geka. 1987 Apr;15(4):375-9.
2
Intracranial aneurysms in patients 18 years of age or under, are they different from aneurysms in adult population?18岁及以下患者的颅内动脉瘤与成年人群中的动脉瘤有区别吗?
Acta Neurochir (Wien). 2005 May;147(5):469-76; discussion 476. doi: 10.1007/s00701-005-0481-y.
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Endovascular embolization vs surgical clipping in treatment of cerebral aneurysms: morbidity and mortality with short-term outcome.血管内栓塞术与外科夹闭术治疗脑动脉瘤的比较:发病率、死亡率及短期预后
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[Intracranial aneurysms and subarachnoid hemorrhage in children and adolescents].[儿童和青少年颅内动脉瘤与蛛网膜下腔出血]
Minerva Med. 1986 Jun 16;77(25):1145-51.
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The impact of microsurgical fenestration of the lamina terminalis on shunt-dependent hydrocephalus and vasospasm after aneurysmal subarachnoid hemorrhage.终板显微开窗术对动脉瘤性蛛网膜下腔出血后分流依赖性脑积水和血管痉挛的影响。
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A randomized trial of intraoperative, intracisternal tissue plasminogen activator for the prevention of vasospasm.术中脑池内注射组织型纤溶酶原激活剂预防血管痉挛的随机试验
Neurosurgery. 1995 Jul;37(1):168-76; discussion 177-8.
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[Study of ruptured intracranial aneurysms with intracerebral hematomas--with special reference to operative indication].颅内动脉瘤破裂伴脑内血肿的研究——特别参考手术指征
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[Correlation of vasospasm with operative results in ruptured aneurysms].[血管痉挛与破裂动脉瘤手术结果的相关性]
No Shinkei Geka. 1982 Aug;10(8):823-9.
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[Temporary occlusion in surgical management of intracranial aneurysm. Report of 54 cases].[颅内动脉瘤手术治疗中的临时阻断。54例报告]
Neurochirurgie. 1999 Mar;45(1):24-8.
10
[Dolichoectatic intracranial arteries. Advances in images and therapeutics].[颅内动脉延长扩张症。影像学与治疗进展]
Medicina (B Aires). 1995;55(1):59-68.

引用本文的文献

1
Effect of Age on Transcranial Doppler Velocities in Patients with Aneurysmal Subarachnoid Hemorrhage.年龄对动脉瘤性蛛网膜下腔出血患者经颅多普勒速度的影响。
Eur Neurol. 2016;76(5-6):261-266. doi: 10.1159/000452273. Epub 2016 Oct 21.
2
Transcranial Doppler diagnosis of cerebral vasospasm following subarachnoid haemorrhage: correlation and analysis of results in relation to the age of patients.经颅多普勒超声诊断蛛网膜下腔出血后脑血管痉挛:与患者年龄相关的结果相关性及分析
Acta Neurochir (Wien). 1994;127(1-2):32-6. doi: 10.1007/BF01808543.