Aoyagi N, Hayakawa I, Iai S, Tsuchida T, Furihata S
No Shinkei Geka. 1985 May;13(5):511-8.
We reviewed 40 cases of intracranial ruptured aneurysm with intracerebral hematoma (An-ICH) and compared those with 177 cases of intracranial single ruptured aneurysm causing only subarachnoid hemorrhage (An-SAH). An-ICH accounted 11.6% of the intracranial aneurysm, ruptured at the mean age of 54 years, and occurred equally in both sexes. The localization of An-ICH was 50% in the middle cerebral artery (MC), 43% in the anterior cerebral artery (AC) and 8% in the internal carotid arterial region. Forty percent of An-ICH were treated conservatively and the outcome was very misery (no useful life and 94% was poor or dead). Sixty percent of An-ICH were treated surgically (neck-clipping and removal of the hematoma) and the outcome was poor (17% useful life and 46% poor and dead). Especially in MC aneurysm, operability was 85% and post-operative useful life was 12% and post-operative poor or dead was 53%. In AC aneurysm, operability was 35% and post-operative useful life was 33% and poor or dead was 33%. These miserable results raised a question of operative indication for An-ICH. The five clinical indices (decerebration, hypertension greater than or equal to 200 mmHg, Hunt-Hess grade V, anisocoria in AC, severe shift of midline structure on X-CT) were selected, because any patients who presented with even only one of them became fatal or vegetative state regardless of conservative or surgical treatment. Assuming them as the non-operative standards, operability decreased in 35% MC, 29% AC, useful life outcome came up to 20% MC, 40% AC, and misery outcome came down to 20% MC, 20% AC.(ABSTRACT TRUNCATED AT 250 WORDS)
我们回顾了40例伴有脑内血肿的颅内破裂动脉瘤(An-ICH)患者,并将其与177例仅导致蛛网膜下腔出血的颅内单发破裂动脉瘤(An-SAH)患者进行比较。An-ICH占颅内动脉瘤的11.6%,破裂时平均年龄为54岁,男女发病率相同。An-ICH的位置分布为:大脑中动脉(MC)占50%,大脑前动脉(AC)占43%,颈内动脉区域占8%。40%的An-ICH患者接受保守治疗,预后极差(无有效生存期,94%预后不良或死亡)。60%的An-ICH患者接受手术治疗(夹闭瘤颈并清除血肿),预后也很差(17%有有效生存期,46%预后不良或死亡)。特别是在MC动脉瘤中,手术可操作性为85%,术后有效生存期为12%,术后预后不良或死亡为53%。在AC动脉瘤中,手术可操作性为35%,术后有效生存期为33%,预后不良或死亡为33%。这些令人沮丧的结果引发了关于An-ICH手术指征的问题。选择了五个临床指标(去大脑强直、血压大于或等于200 mmHg、Hunt-Hess分级为V级、AC区瞳孔不等大、X线CT显示中线结构严重移位),因为任何出现其中一项指标的患者,无论接受保守治疗还是手术治疗,都会死亡或进入植物人状态。将这些指标作为非手术标准后,MC动脉瘤的可操作性下降了35%,AC动脉瘤下降了29%;MC动脉瘤的有效生存期提高到20%,AC动脉瘤提高到40%;MC动脉瘤的不良预后下降到20%,AC动脉瘤下降到20%。(摘要截选至250字)