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[脊髓硬膜外脑膜瘤——一例报告并特别提及神经放射学表现]

[Spinal epidural meningioma--a case report with special reference to neuroradiological findings].

作者信息

Kyoushima K, Nishiura I, Koyama T

出版信息

No Shinkei Geka. 1987 Apr;15(4):443-9.

PMID:3614538
Abstract

Spinal meningiomas are common as intradural-extramedullary neoplasm, but solitaly epidural spinal meningiomas are extremely rare. They may often be misdiagnosed as malignant neoplasms which are much more common in this location. Furthermore, at the time of operation, it is often difficult to distinguish the epidural meningioma from malignant tumors, even by the microscopic examination of the fresh frozen section. We present a case of spinal epidural meningioma, and emphasize the importance of preoperative neuroradiological examinations. A 26-year-old woman was referred to us from a neurologist of another hospital under the diagnosis of thoracic spinal tumor. She noticed sensory numbness in the lower extremities and thermal hypesthesia below the breasts about one year previously, and progressive gait disturbance about half a year prior to admission. Neurological examination revealed spastic paraparesis with hypesthesia of all modalities below T3. Plain films of the thoracic spine showed scalloping of the posterior margine of the T3 vertebral body. Metrizamide myelography showed a complete block at T3/4, and metrizamide CT revealed marked dural compression by an epidural mass which occupied the left side of the spinal canal from T2 to T4. The subarachnoid space all around the spinal cord was preserved comparatively well. The tumor was homogeneously enhanced by intravenous contrast enhanced CT scan, and the extracanalicular extension was not revealed. MRI [SE (400/25)] showed an iso-intensity signal tumor. Neither extracanalicular nor intrathecal extension of the tumor was showed. In addition to the possibility of the malignant tumors, we considered the possibility of spinal epidural meningioma. At operation, of highly vascularized, moderately firm epidural tumor was found invading the surrounding epidural fat.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

脊髓脑膜瘤是常见的硬脊膜内髓外肿瘤,但孤立性硬膜外脊髓脑膜瘤极为罕见。它们常被误诊为在该部位更为常见的恶性肿瘤。此外,在手术时,即使通过新鲜冰冻切片的显微镜检查,也常常难以将硬膜外脑膜瘤与恶性肿瘤区分开来。我们报告一例脊髓硬膜外脑膜瘤病例,并强调术前神经放射学检查的重要性。一名26岁女性由另一家医院的神经科医生转诊至我院,诊断为胸椎肿瘤。她大约一年前开始注意到下肢感觉麻木及乳房以下温度觉减退,入院前半年出现进行性步态障碍。神经系统检查显示T3以下痉挛性截瘫伴各种感觉减退。胸椎平片显示T3椎体后缘呈扇贝样改变。甲泛葡胺脊髓造影显示T3/4水平完全梗阻,甲泛葡胺CT显示硬膜外肿块明显压迫硬膜,该肿块占据T2至T4水平椎管左侧。脊髓周围蛛网膜下腔保存相对良好。静脉注射对比剂增强CT扫描显示肿瘤均匀强化,未发现椎管外扩展。MRI[SE(400/25)]显示肿瘤呈等信号。未显示肿瘤的椎管外或鞘内扩展。除了恶性肿瘤的可能性外,我们还考虑了脊髓硬膜外脑膜瘤的可能性。手术中发现一个血管丰富、质地中等坚实的硬膜外肿瘤侵犯周围硬膜外脂肪。(摘要截短至250字)

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