Borni Mehdi, Abdelmouleh Souhir, Mechergui Haifa, Elouni Emna, Boudawara Mohamed Zaher
Department of Neurosurgery - UHC Habib Bourguiba -Sfax, Tunisia.
Ann Med Surg (Lond). 2022 Aug 19;81:104451. doi: 10.1016/j.amsu.2022.104451. eCollection 2022 Sep.
and importance: Propionibacterium acnes (P. acnes) is an anaerobic, lipophilic, Gram-positive bacteria of the commensal skin flora. It may also be present on the mouth's mucosa, nose, urogenital tract, and large bowel. P. acnes is an unusual and rare agent of intracerebral abscess although in recent years some publications suggest that its frequency in brain surgery is increasing.
The authors report a case of an incidental cerebral abscess during follow-up imaging in a 63-year-old male patient operated on twice for cerebral meningioma the last of which was 3 months ago without placement of any surgical implant with uneventful postoperative course.
P. acnes is still an sunder-appreciated cause of post-neurosurgical infection. Time between neurosurgery and infection is variable ranging from few months to many years. Its culture time is long, with currently an average time to positivity of six days (2-15 days), justifying prolonged cultures.
Intracranial infections by P. acnes are not quite frequent. We emphasize the need to send samples for culture of anaerobes in this type of complications before giving a negative result.
及重要性:痤疮丙酸杆菌是共生皮肤菌群中的一种厌氧、嗜脂、革兰氏阳性菌。它也可能存在于口腔黏膜、鼻子、泌尿生殖道和大肠。痤疮丙酸杆菌是脑内脓肿的一种不常见且罕见的病原体,尽管近年来一些出版物表明其在脑外科手术中的发生率正在增加。
作者报告了一例63岁男性患者在随访成像期间偶然发现脑脓肿的病例,该患者曾因脑膜瘤接受过两次手术,最后一次手术是在3个月前,未植入任何手术植入物,术后病程平稳。
痤疮丙酸杆菌仍然是神经外科手术后感染的一个未得到充分认识的原因。神经外科手术与感染之间的时间间隔各不相同,从几个月到多年不等。其培养时间很长,目前平均阳性时间为6天(2 - 15天),这使得延长培养时间是合理的。
痤疮丙酸杆菌引起的颅内感染并不常见。我们强调在这类并发症中,在得出阴性结果之前,有必要送检样本进行厌氧菌培养。