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灌注指数与视觉模拟评分法:作为急诊科肾绞痛疼痛的客观评估工具

Perfusion index versus visual analogue scale: as an objective tool of renal colic pain in emergency department.

作者信息

Gulen Muge, Satar Salim, Acehan Selen, Yildiz Derviş, Aslanturkiyeli Ebru Funda, Aka Satar Deniz, Kucukceylan Melike

机构信息

Adana City Training and Research Hospital, Department of Emergency Medicine, Adana, Turkey.

Iskenderun State Hospital, Department of Emergency Medicine, Hatay, Turkey.

出版信息

Heliyon. 2022 Sep 14;8(9):e10606. doi: 10.1016/j.heliyon.2022.e10606. eCollection 2022 Sep.

Abstract

BACKGROUND

Perfusion index (PI) has use to monitor sympathetic response changes to pain. In this study, we aimed to evaluate the utility of using perfusion index as an objective marker of pain relief and of the need for rescue analgesia in ED patients with documented renal colic.

METHODS

We conducted a prospective observational study between January 2020 and December 2020. The demographic characteristics of the patients, their complaints, nephrolithiasis histories, vital signs, PI, and VAS scores (on admission and after treatment) were recorded.

RESULTS

A total of 144 patients were included. All patients were administered 20 mg of Tenoxicam on admission. There was a statistically significant difference between the PI (<0.001) and VAS scores (<0.001) on admission and after the administration of Tenoxicam. 43.1% (n = 62) of the patients needed rescue analgesia. Accordingly to ROC curve, the ability of both PI (AUC: 0.615, 95%CI 0.519-0.711, p = 0.018) and ΔPI (AUC: 0.601, 95%CI 0.508-0.694, p = 0.039) indices were determined as statistically significant. The cutoff value of the PI level for the prediction of the needed rescue analgesia was 4.65 and the cutoff value for ΔPI (PIPI) was 2. All patients had a pain VAS score of <3 and a mean PI of 5.7 ± 2.9 at discharge from the emergency department.

CONCLUSION

In patients presenting to the emergency department with renal colic, the PI value on admission and after analgesic therapy can be helpful in assessing the severity of pain and predict the need for rescue analgesia.

摘要

背景

灌注指数(PI)已被用于监测对疼痛的交感神经反应变化。在本研究中,我们旨在评估在有记录的肾绞痛急诊患者中,使用灌注指数作为疼痛缓解和急救镇痛需求的客观指标的效用。

方法

我们在2020年1月至2020年12月期间进行了一项前瞻性观察研究。记录患者的人口统计学特征、主诉、肾结石病史、生命体征、PI和VAS评分(入院时和治疗后)。

结果

共纳入144例患者。所有患者入院时均给予20mg替诺昔康。入院时与给予替诺昔康后,PI(<0.001)和VAS评分(<0.001)之间存在统计学显著差异。43.1%(n = 62)的患者需要急救镇痛。根据ROC曲线,PI(AUC:0.615,95%CI 0.519 - 0.711,p = 0.018)和ΔPI(AUC:0.601,95%CI 0.508 - 0.694,p = 0.039)指标的能力被确定为具有统计学显著性。预测所需急救镇痛的PI水平截断值为4.65,ΔPI(PIPI)的截断值为2。所有患者出院时疼痛VAS评分<3,平均PI为5.7±2.9。

结论

对于因肾绞痛就诊于急诊科的患者,入院时和镇痛治疗后的PI值有助于评估疼痛严重程度并预测急救镇痛的需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12b3/9485029/c6eaf799d7f6/gr1.jpg

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