School of life Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, P. R. China.
School of Chemical Sciences, University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
Org Biomol Chem. 2022 Oct 5;20(38):7599-7603. doi: 10.1039/d2ob01539k.
A catalytic charge transfer complex strategy that enabled difluoromethylation and ethoxycarbonylmonofluoromethylation of enamides with phosphonium bromine salts has been reported. This strategy also provides a convenient approach for the synthesis of functionalized oxindoles and 1,1-diphenylethylenes with easily available phosphonium bromine salts and a catalytic amount of iodine anion.
一种通过催化电荷转移复合物策略，实现了磷溴盐对烯酰胺的二氟甲基化和乙氧羰基单氟甲基化的方法已经被报道。该策略还提供了一种方便的方法，通过使用易得的磷溴盐和催化量的碘阴离子，合成功能化的吲哚啉和 1,1-二苯基乙烯。
