Department of Urology, Cochin Hospital, Assistance Publique-Hôpitaux de Paris, Paris Descartes University, Paris, France.
Skin and Laser Center, Scin Center Cassel, Kassel, Germany.
Acta Dermatovenerol Alp Pannonica Adriat. 2022 Sep;31(3):123-124.
Scrotal calcinosis is a rare disorder characterized by multiple papules or nodules of calcification in the scrotal skin. The pathogenesis of this disease is poorly understood. The condition presents as several brown to yellowish asymptomatic nodules on the scrotum. Excision followed by scrotal reconstruction is the treatment of choice. It leaves a good cosmetic result with low chances of recurrence. Newer treatments, such as ablative lasers, have been proposed with very good results. We describe the case of a 28-year-old patient with a history of severe acne treated with oral isotretinoin that presented for scrotal nodules. On laboratory examination, hypercalcemia was found with normal phosphorus, parathyroid hormone, and vitamin D hormone levels. Hypercalcemia was linked to his isotretinoin therapy. Serum calcium concentrations normalized after cessation of isotretinoin and hydration. Because the patient refused surgery, a biopsy of the lesion confirmed the diagnosis of scrotal calcinosis. Then the patient was referred to a cosmetic laser center to treat his condition.
阴囊钙化症是一种罕见的疾病，其特征是阴囊皮肤有多个钙质沉着的丘疹或结节。这种疾病的发病机制尚不清楚。这种疾病表现为阴囊上有几个棕色到黄色的无症状结节。切除后进行阴囊重建是首选的治疗方法。它的美容效果很好，复发的几率很低。新的治疗方法，如消融激光，已经提出，并取得了很好的效果。我们描述了一名 28 岁的患者，他有严重痤疮的病史，曾接受过口服异维 A 酸治疗，他因阴囊结节就诊。实验室检查发现血钙升高，磷、甲状旁腺激素和维生素 D 激素水平正常。高钙血症与他的异维 A 酸治疗有关。停止异维 A 酸治疗和补液后，血清钙浓度恢复正常。由于患者拒绝手术，对病变进行了活检，以明确阴囊钙化症的诊断。然后，患者被转介到美容激光中心治疗他的病情。
