Yao Hai-Jun, Zheng Da-Chao, Xie Min-Kai, Chen Jun, Mao Yuan-Shen, Wan Xiang, Jiang Yue-Qing, Ren Xiao-Min, Wang Zhong
Department of Urology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Department of Dermatology, Shanghai 9th People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China.
Zhonghua Nan Ke Xue. 2019 Jun;25(6):544-548.
To investigate the clinical features, pathogenesis, diagnosis and scrotal reconstruction in the treatment of idiopathic scrotal calcinosis (ISC).
From March 2007 to October 2018, 10 ISC patients, aged 28－79 (mean 45) years and with a disease course of 6－497 (mean 128.4) months, were treated in our hospital. We retrospectively analyzed their clinical data and reviewed related literature.
All the patients underwent physical examination and biochemical and parathyroid function tests. None of them had a history of endocrine or metabolic disease, or trauma, or a family member with similar diseases, and none had subjective symptoms except local pruritus in 1 case. All were treated surgically and post-operative follow-up revealed no recurrence. Histopathological examination of the excised lesion confirmed it to be ISC.
ISC is a rare localized benign disease, of which surgery seems an effective option for the definite diagnosis and treatment. Occasionally scrotal reconstruction may be required in case of extensive involvement of the scrotal skin.
探讨特发性阴囊钙质沉着症（ISC）的临床特征、发病机制、诊断及阴囊重建治疗方法。
2007年3月至2018年10月，我院收治10例ISC患者，年龄28 - 79岁（平均45岁），病程6 - 497个月（平均128.4个月）。我们回顾性分析了他们的临床资料并复习相关文献。
所有患者均接受了体格检查、生化及甲状旁腺功能检查。他们均无内分泌或代谢疾病史、外伤史，也无家族成员患类似疾病，除1例有局部瘙痒外均无主观症状。所有患者均接受手术治疗，术后随访无复发。切除病变组织的组织病理学检查确诊为ISC。
ISC是一种罕见的局限性良性疾病，手术似乎是明确诊断和治疗的有效选择。若阴囊皮肤广泛受累，偶尔可能需要进行阴囊重建。
