Department of Bio-convergence Engineering, Korea University, Seoul; Proton Therapy Center, National Cancer Center, Goyang, Korea.
Department of Bio-convergence Engineering, Korea University, Seoul, Korea.
J Cancer Res Ther. 2022 Jul-Sep;18(4):1152-1158. doi: 10.4103/jcrt.JCRT_8_20.
This study describes a simple method of inter-fractional photon beam monitoring to measure the entrance dose of radiation treatment using Gafchromic EBT3 film.
The film was placed at the center of a 1-cm thick phantom shaped like a block tray and fixed on the accessory tray of the gantry. The entrance dose was measured following the placement of the film in the accessory tray. The dose distribution calculated with the treatment planning system was compared with the dose distribution on the irradiated EBT3 films. The effectiveness of this methodology, as determined by gamma passing rates, was evaluated for the 22 fields of eight three-dimensional conformal radiotherapy (3D-CRT) plans and the 41 fields of nine intensity-modulated radiotherapy (RT) plans. The plans for three-dimensional conformal RT included treatments of the rectum, liver, breast, and head and neck, whereas the plans for intensity-modulated RT included treatments of the liver, brain, and lung.
The gamma passing rates for 3D-CRT ranged from 96.4% to 99.5%, with the mean gamma passing rate for 22 fields being 98.0%. The gamma passing rate for intensity-modulated RT ranged from 96.1% to 98.9%, with the mean gamma passing rate for 41 fields being 97.7%. All gamma indices were over the 95% tolerance level.
The methodology described in this study, based on Gafchromic EBT3 film, can be utilized for inter-fractional entrance dose monitoring as quality assurance during RT. Clinical application of this method to patients can verify the accuracy of beam delivery in the treatment room.
本研究描述了一种简单的光子束分次剂量监测方法,使用 Gafchromic EBT3 胶片测量放射治疗的入射剂量。
将胶片放置在一个 1 厘米厚的、形状像托盘的体模中心,并固定在旋转机架的附件托盘上。在附件托盘上放置胶片后测量入射剂量。用治疗计划系统计算的剂量分布与照射后的 EBT3 胶片的剂量分布进行比较。用伽马通过率评估这种方法的有效性,对 8 个三维适形放射治疗(3D-CRT)计划的 22 个射野和 9 个调强放射治疗(IMRT)计划的 41 个射野进行了评估。三维适形 RT 计划包括直肠、肝脏、乳房和头颈部的治疗,而调强 RT 计划包括肝脏、脑部和肺部的治疗。
3D-CRT 的伽马通过率范围为 96.4%至 99.5%,22 个射野的平均伽马通过率为 98.0%。调强 RT 的伽马通过率范围为 96.1%至 98.9%,41 个射野的平均伽马通过率为 97.7%。所有伽马指数均超过 95%的容限水平。
本研究描述的基于 Gafchromic EBT3 胶片的方法可用于调强放疗中的分次入射剂量监测,作为放疗质量保证的手段。将这种方法应用于患者的临床,可以验证治疗室内光束传输的准确性。