Magni Guido, Merskey Harold
Department of Psychiatry, University of Western Ontario, London, Ont. N6A 4H1 Canada.
Pain. 1987 Jun;29(3):295-300. doi: 10.1016/0304-3959(87)90044-3.
It is often assumed that pain can be caused by psychological illness and also that severely painful organic lesions may cause emotional change. If these assumptions are correct, pain in the absence of lesions should be associated with a very high rate of psychiatric diagnosis; pain with lesions should occur with psychological illness more often than by chance but less often than in the group without lesions. To test these hypotheses two groups have been compared, one with pain and no evidence of organic lesions, the other with pain proportionate to organic lesions. Ninety-seven per cent of the first group and 39% of the second group were found to have psychiatric conditions (P less than 0.001).
人们常常认为，心理疾病会引发疼痛，严重的器质性病变也可能导致情绪变化。如果这些假设正确，那么无病变情况下的疼痛应该与极高的精神疾病诊断率相关；有病变的疼痛出现心理疾病的几率应高于偶然情况，但低于无病变组。为验证这些假设，对两组进行了比较，一组有疼痛但无器质性病变证据，另一组的疼痛与器质性病变程度相符。结果发现，第一组中有97%的人患有精神疾病，第二组为39%（P<0.001）。
