Department of Neurology, The Second Affiliated Hospital of Zhengzhou University, Zhengzhou, 450053, Henan Province, China.
Department of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Xuhui District, Shanghai, 200233, China.
Adv Ther. 2022 Dec;39(12):5401-5412. doi: 10.1007/s12325-022-02312-0. Epub 2022 Sep 24.
This study investigated the effect of sound therapy combined with drug therapy (SDT) on gap detection threshold and speech recognition scores in patients with sudden sensorineural hearing loss (SSNHL).
Patients with SSNHL were grouped randomly into SDT and drug therapy (DT) groups. All patients received standard drug treatment and patients in the SDT group additionally received sound stimulation for the affected ears for 6 days. Pure tone audiogram, speech recognition scores at normal and time-compressed rates under quiet and noisy conditions, and the gap detection threshold of the SDT and DT groups before treatment and on day 6 and 30 after treatment were compared.
There were 20 patients in the SDT group and 24 in the DT group. The pure tone thresholds of affected ears were significantly lower in the SDT group on day 6 after treatment than those in the DT group at 125 and 250 Hz. Significantly lower gap detection thresholds and higher speech recognition scores under noisy conditions were observed at the normal and time-compressed rates in the SDT group than those in the DT group on day 6 and 30 after treatment. Significant correlations were observed between the gap thresholds and speech recognition scores in a noisy environment at normal and time-compressed rates on day 6 and 30.
SDT may improve the recovery of hearing abilities, such as the gap in noise thresholds and speech recognition in noise, in the case of SSNHL.
ChiCTR-IOR-17012262.
本研究旨在探讨声治疗联合药物治疗(SDT)对突发性聋患者的听阈间隙和言语识别评分的影响。
将突发性聋患者随机分为 SDT 组和药物治疗(DT)组。所有患者均接受标准药物治疗,SDT 组患者同时接受患耳声音刺激,共 6 天。比较两组患者治疗前、治疗后第 6 天和第 30 天的纯音听阈、安静和噪声环境下正常和时间压缩率言语识别评分,以及 SDT 和 DT 组的听阈间隙。
SDT 组 20 例,DT 组 24 例。治疗后第 6 天,SDT 组患耳纯音听阈在 125 和 250 Hz 时明显低于 DT 组。治疗后第 6 天和第 30 天,SDT 组在正常和时间压缩率下噪声环境中的听阈间隙和言语识别评分均明显高于 DT 组。治疗后第 6 天和第 30 天,正常和时间压缩率噪声环境下的听阈间隙和言语识别评分呈显著相关。
SDT 可能改善突发性聋患者的听力恢复能力,如噪声环境下的听阈间隙和言语识别。
ChiCTR-IOR-17012262。