Visconti Michael J, Archibald Laura K, Shahwan Kathryn T, Kimyon Rebecca S, Bakker Caitlin, Mattox Adam R, Alam Murad, Maher Ian A
Department of Dermatology, St. Joseph Mercy, Ann Arbor, MI, USA.
Department of Dermatology, University of Minnesota, Phillips-Wangensteen Building, 516 Delaware Street SE, Suite 4-240, Minneapolis, MN, 55455, USA.
Arch Dermatol Res. 2023 Apr;315(3):333-337. doi: 10.1007/s00403-022-02390-8. Epub 2022 Sep 24.
Numerous reconstructive techniques for nasal defects following skin cancer removal have been described; however, the literature lacks a comprehensive systematic review. Our objective was to systematically review nasal reconstruction methods after tumor removal, correlate the use of specific techniques to the nasal subunits involved, assess the quality of the available evidence, and set the stage for future research on this topic. Eight databases were searched for studies published in English from January 2004 to December 2018 containing repair data for nasal defects following Mohs or excision for four or more subjects. Recorded data included author specialties, study design, subject number, demographics, defect characteristics, procedure type, reconstructive methods, outcome measures, and complications. One-hundred and eleven studies were included. Study types included case series (73%), observational cohort studies (25%), and clinical trials (2%). Most authors were dermatologic surgeons (61%). Resection was most commonly performed via Mohs (82%). Flaps (42%), linear closures (28%) and grafts (25%) were most utilized for reconstruction. In Zones I and II, transposition flaps were the most common followed by advancement flaps. In Zone III, full thickness skin grafts were the most common repair. Most studies were case series or small cohort studies, representing low level evidence. Flaps are the most common method described in the literature for nasal reconstruction. The overall quality of the evidence available on this topic is low.
已有诸多关于皮肤癌切除术后鼻缺损的重建技术被描述;然而,文献中缺乏全面的系统评价。我们的目的是系统评价肿瘤切除术后的鼻重建方法,将特定技术的应用与受累的鼻亚单位相关联,评估现有证据的质量,并为该主题的未来研究奠定基础。检索了八个数据库,以查找2004年1月至2018年12月期间以英文发表的、包含针对四名或更多受试者的Mohs手术或切除术后鼻缺损修复数据的研究。记录的数据包括作者专业、研究设计、受试者数量、人口统计学、缺损特征、手术类型、重建方法、结局指标和并发症。纳入了111项研究。研究类型包括病例系列(73%)、观察性队列研究(25%)和临床试验(2%)。大多数作者是皮肤科外科医生(61%)。切除最常通过Mohs手术进行(82%)。皮瓣(42%)、直线缝合(28%)和移植(25%)是最常用的重建方法。在I区和II区,易位皮瓣最常见,其次是推进皮瓣。在III区,全厚皮片移植是最常见的修复方法。大多数研究是病例系列或小型队列研究,证据水平较低。皮瓣是文献中描述的最常见的鼻重建方法。关于该主题的现有证据的总体质量较低。