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Mohs 显微外科手术在具有挑战性的解剖部位。

Mohs Micrographic Surgery at Challenging Anatomical Sites.

机构信息

*All authors are affiliated with the Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.

All authors are affiliated with the Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.

出版信息

Dermatol Surg. 2019 Dec;45 Suppl 2:S142-S154. doi: 10.1097/DSS.0000000000002255.

DOI:10.1097/DSS.0000000000002255
PMID:31764299
Abstract

BACKGROUND

Mohs micrographic surgery (MMS) is often the treatment of choice for skin cancer removal as it maximizes normal tissue sparing and can be paired with a reconstructive approach that optimizes function and cosmesis. Many tumors on the eyelid, nose, ear, and genitals are particularly well suited for MMS but can be challenging for the dermatologic surgeon.

OBJECTIVE

To review the complex anatomy, as well as the authors' approach to executing and interpreting Mohs layers, at each of these anatomical sites.

METHODS

A review of the literature on MMS of the eyelid, nose, ear, and genitals was performed using the PubMed database and relevant search terms.

CONCLUSION

These sites present potential pitfalls for tumor resection and reconstruction, but with the proper technique, the dermatologic surgeon can minimize tumor recurrence and MMS complications. Warning signs for potentially difficult tumor resection can signify when an interdisciplinary approach is warranted.

摘要

背景

Mohs 显微外科手术(MMS)通常是皮肤癌切除的首选治疗方法,因为它最大限度地保留了正常组织,并可以与重建方法相结合,从而优化功能和美容效果。眼睑、鼻子、耳朵和生殖器上的许多肿瘤特别适合 MMS,但对皮肤科医生来说具有挑战性。

目的

回顾在这些解剖部位执行和解释 Mohs 层的复杂解剖结构以及作者的方法。

方法

使用 PubMed 数据库和相关搜索词对眼睑、鼻子、耳朵和生殖器的 MMS 文献进行综述。

结论

这些部位在肿瘤切除和重建方面存在潜在的陷阱,但通过正确的技术,皮肤科医生可以最大限度地减少肿瘤复发和 MMS 并发症。潜在困难的肿瘤切除的警告信号表明何时需要采用多学科方法。

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引用本文的文献

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Adv Ther. 2025 Sep 18. doi: 10.1007/s12325-025-03354-w.
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Mohs micrographic surgery challenges and new technologies to optimize care of cutaneous malignancies of the ear.Mohs 显微外科手术挑战与新技术,优化耳部皮肤恶性肿瘤的治疗。
Arch Dermatol Res. 2024 Jun 1;316(6):320. doi: 10.1007/s00403-024-03127-5.
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90-degree incision in Mohs micrographic surgery for eyelid margin tumors - Is there a benefit?
用于眼睑边缘肿瘤的莫氏显微外科手术中的90度切口——有什么益处吗?
An Bras Dermatol. 2024 Jan-Feb;99(1):115-117. doi: 10.1016/j.abd.2023.06.002. Epub 2023 Sep 22.
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Nasal reconstructive techniques following Mohs surgery or excisions: a systematic review.莫氏手术或切除术后的鼻重建技术:一项系统评价
Arch Dermatol Res. 2023 Apr;315(3):333-337. doi: 10.1007/s00403-022-02390-8. Epub 2022 Sep 24.
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Combined Mohs Micrographic Surgery in a Collision Tumor.联合莫氏显微外科手术治疗碰撞瘤
Cureus. 2022 Jul 11;14(7):e26747. doi: 10.7759/cureus.26747. eCollection 2022 Jul.
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