Colón Luis Felipe, Powell Charles, Wilson Andrew, Burgan Taylor, Quigley Robert
Department of Orthopaedic Surgery, University of Tennessee College of Medicine in Chattanooga, 975 E. Third St, Hospital Box 260, Chattanooga, TN, 37403, USA.
Quillen College of Medicine-East Tennessee State University College of Medicine, Johnson City, TN, USA.
Spine Deform. 2023 Mar;11(2):373-381. doi: 10.1007/s43390-022-00587-5. Epub 2022 Sep 24.
To assess effectiveness of a rapid recovery pathway (RRP) without epidural catheter analgesia (ECA) or intravenous patient controlled analgesia (PCA) in accelerating recovery and decreasing opioid consumption in patients with adolescent idiopathic scoliosis (AIS) undergoing posterior spinal fusion (PSF).
A retrospective cohort study included collection of demographics, ECA use, IV PCA, postoperative opioid consumption, postoperative pain scores, and reoperation rate. Opioid consumption was calculated using morphine milligram equivalents (MME). Hospital length of stay (HLOS) and first reported ambulation with physical therapy (PT) were also recorded.
53 patients were included, with 18 in the RRP group. Patient characteristics were comparable between the groups, except in ECA use and BMI. The RRP group consumed less total MME from postoperative day (POD) 0 to 2 (mean difference 61.6 MME; 95% CI 37.1-86.1 MME; p < 0.001). In addition, the RRP group had significantly shorter HLOS (2.5 vs 4.0 days; p < 0.001). There were no differences in VAS scores between the two groups. A subset analysis comparing patients who did and did not receive ECA showed that ECA resulted in overall higher inpatient MME and HLOS. A prediction model was developed using multiple regression based on the different medications used for multimodal analgesia (MMA) in the RRP.
An RRP without the use of ECA or IV PCA can provide adequate analgesia in patients with AIS undergoing PSF while lowering inpatient narcotic consumption and accelerating immediate postoperative recovery.
评估在青少年特发性脊柱侧凸(AIS)患者行后路脊柱融合术(PSF)时,不使用硬膜外导管镇痛(ECA)或静脉自控镇痛(PCA)的快速康复路径(RRP)在加速康复和减少阿片类药物消耗方面的有效性。
一项回顾性队列研究,收集人口统计学资料、ECA使用情况、静脉PCA、术后阿片类药物消耗、术后疼痛评分和再次手术率。使用吗啡毫克当量(MME)计算阿片类药物消耗。还记录了住院时间(HLOS)和首次报告的物理治疗(PT)下床活动情况。
纳入53例患者,RRP组18例。除ECA使用情况和体重指数(BMI)外,两组患者特征具有可比性。RRP组术后第0天至第2天的总MME消耗量较少(平均差异61.6 MME;95%置信区间37.1 - 86.1 MME;p < 0.001)。此外,RRP组的HLOS明显更短(2.5天对4.0天;p < 0.001)。两组之间视觉模拟评分(VAS)无差异。一项比较接受和未接受ECA患者的亚组分析表明,ECA导致总体住院MME和HLOS更高。基于RRP中用于多模式镇痛(MMA)的不同药物,使用多元回归建立了一个预测模型。
不使用ECA或静脉PCA的RRP可为行PSF的AIS患者提供充分镇痛,同时降低住院患者麻醉药物消耗并加速术后即刻康复。