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新型冠状病毒肺炎与肺癌:最新筛查、诊断、治疗及挑战。

COVID-19 and lung cancer: update on the latest screening, diagnosis, management and challenges.

机构信息

Department of Internal Medicine, Division of Hematology and Oncology, Naef K. Basile Cancer Institute, 66984, American University of Beirut Medical Center, Beirut, Lebanon.

Department of Internal Medicine, 37608, Saint George Hospital University Medical Center, Beirut, Lebanon.

出版信息

J Int Med Res. 2022 Sep;50(9):3000605221125047. doi: 10.1177/03000605221125047.

Abstract

Lung cancer, considered one of the most common causes of cancer deaths worldwide, is a complex disease with its own challenges. The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), compounded these challenges and forced the medical healthcare system to alter its approach to lung cancer. This narrative review aims to identify the effect of the COVID-19 pandemic on lung cancer screening, diagnosis and management. During this public health crisis, various medical societies have worked on developing guidelines to protect patients with lung cancer from the deleterious effects of SARS-CoV-2 infection, as well as from the complications imposed by treatment delays. The different therapeutic approaches, such as surgery, radiation oncology and immune checkpoint inhibitor therapy, along with the latest international recommendations, will be discussed. Protecting patients with lung cancer from COVID-19 complications, while avoiding barriers in treatment delays, has brought unique challenges to healthcare facilities. Prompt modifications to guidelines, and constant evaluation of their efficacy, are thus needed.

摘要

肺癌是全球最常见的癌症死因之一,是一种具有自身挑战的复杂疾病。由严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的 2019 年冠状病毒病(COVID-19)大流行使这些挑战更加复杂,并迫使医疗保健系统改变其治疗肺癌的方法。本叙述性评论旨在确定 COVID-19 大流行对肺癌筛查、诊断和管理的影响。在这场公共卫生危机期间,各个医学协会一直在制定指南,以保护肺癌患者免受 SARS-CoV-2 感染的有害影响,以及治疗延迟带来的并发症。将讨论不同的治疗方法,如手术、放射肿瘤学和免疫检查点抑制剂治疗,以及最新的国际建议。保护肺癌患者免受 COVID-19 并发症的影响,同时避免治疗延迟带来的障碍,给医疗机构带来了独特的挑战。因此,需要及时修改指南,并不断评估其疗效。

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