Mangone Lucia, Marinelli Francesco, Bisceglia Isabella, Filice Angelina, De Leonibus Lisa, Rapicetta Cristian, Paci Massimiliano
Epidemiology Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Nuclear Medicine Unit, Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, 42122 Reggio Emilia, Italy.
Biology (Basel). 2023 Feb 28;12(3):390. doi: 10.3390/biology12030390.
The COVID-19 pandemic has had a significant impact on new cancer diagnoses. This study aims to evaluate the implications of the lockdown period on new lung cancer diagnoses in northern Italy. We compared 2020 with 2019 cancer registry data, reporting the variations by age, stage, and treatments. In 2020, 303 lung cancer cases were registered, 21 fewer than in 2019. Cases fell in men (-31 patients, 9.6%) but not in women (+10 patients, +3.1%). A significant drop in stage I from 19.8% to 12.9% ( < 0.05) and an increase in stage III (12.7% vs. 19.1%; < 0.05) was observed. Histological confirmation dropped (70.1% vs. 60.1%; < 0.05) while cytology increased (12% vs. 20.8%; < 0.01). Surgery declined (28.7% vs. 21.5%; < 0.05) but increased in stage III (19.5% vs. 25.9%; = 0.46), while chemotherapy increased (17.6% vs. 34.3%; < 0.01) for all stages. During the pandemic, new lung cancer diagnoses dropped only in men. The reorganization of health services has ensured a decrease in surgical interventions (due to the unavailability of operating rooms) counterbalanced by an increase in chemotherapy.
新冠疫情对新发癌症诊断产生了重大影响。本研究旨在评估意大利北部封锁期对新发肺癌诊断的影响。我们将2020年与2019年的癌症登记数据进行了比较，报告了年龄、分期和治疗方面的变化。2020年登记了303例肺癌病例，比2019年减少了21例。男性病例数下降（减少31例，9.6%），但女性病例数未下降（增加10例，3.1%）。观察到I期病例显著下降，从19.8%降至12.9%（<0.05），III期病例增加（12.7%对19.1%；<0.05）。组织学确诊率下降（70.1%对60.1%；<0.05），而细胞学确诊率上升（12%对20.8%；<0.01）。手术率下降（28.7%对21.5%；<0.05），但III期手术率增加（19.5%对25.9%；=0.46），而所有分期的化疗率均上升（17.6%对34.3%；<0.01）。在疫情期间，新发肺癌诊断仅在男性中下降。卫生服务的重组确保了手术干预的减少（由于手术室不可用），同时化疗增加起到了平衡作用。
