Kim Su Young, Kwak Min Seob, Yoon Soon Man, Jung Yunho, Kim Jong Wook, Boo Sun-Jin, Oh Eun Hye, Jeon Seong Ran, Nam Seung-Joo, Park Seon-Young, Park Soo-Kyung, Chun Jaeyoung, Baek Dong Hoon, Choi Mi-Young, Park Suyeon, Byeon Jeong-Sik, Kim Hyung Kil, Cho Joo Young, Lee Moon Sung, Lee Oh Young
Department of Gastroenterology, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Korea.
Division of Gastroenterology, Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
Korean J Gastroenterol. 2022 Sep 25;80(3):115-134. doi: 10.4166/kjg.2022.103.
Colonoscopic polypectomy is effective in decreasing the incidence and mortality of colorectal cancer (CRC). Premalignant polyps discovered during colonoscopy are associated with the risk of metachronous advanced neoplasia. Postpolypectomy surveillance is the most important method for managing advanced metachronous neoplasia. A more efficient and evidence-based guideline for postpolypectomy surveillance is required because of the limited medical resources and concerns regarding colonoscopy complications. In these consensus guidelines, an analytic approach was used to address all reliable evidence to interpret the predictors of CRC or advanced neoplasia during surveillance colonoscopy. The key recommendations state that the high-risk findings for metachronous CRC following polypectomy are as follows: 1) adenoma ≥10 mm in size; 2) 3-5 (or more) adenomas; 3) tubulovillous or villous adenoma; 4) adenoma containing high-grade dysplasia; 5) traditional serrated adenoma; 6) sessile serrated lesion (SSL) containing any grade of dysplasia; 7) serrated polyp of at least 10 mm in size; and 8) 3-5 (or more) SSLs. More studies are needed to fully comprehend the patients who are most likely to benefit from surveillance colonoscopy and the ideal surveillance interval to prevent metachronous CRC.
结肠镜息肉切除术在降低结直肠癌(CRC)的发病率和死亡率方面是有效的。结肠镜检查期间发现的癌前息肉与异时性进展期肿瘤的风险相关。息肉切除术后监测是管理异时性进展期肿瘤的最重要方法。由于医疗资源有限以及对结肠镜检查并发症的担忧,需要一个更有效且基于证据的息肉切除术后监测指南。在这些共识指南中,采用了一种分析方法来处理所有可靠证据,以解释监测结肠镜检查期间CRC或进展期肿瘤的预测因素。关键建议指出,息肉切除术后异时性CRC的高危发现如下:1)腺瘤大小≥10毫米;2)3至5个(或更多)腺瘤;3)管状绒毛状或绒毛状腺瘤;4)含有高级别异型增生的腺瘤;5)传统锯齿状腺瘤;6)含有任何级别异型增生的无蒂锯齿状病变(SSL);7)大小至少为10毫米的锯齿状息肉;以及8)3至5个(或更多)SSL。需要更多研究来全面了解最有可能从监测结肠镜检查中受益的患者以及预防异时性CRC的理想监测间隔。