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介入放射学联合内镜引流治疗高出血风险的胰腺液体积聚:两例病例报告。

Interventional radiology followed by endoscopic drainage for pancreatic fluid collections associated with high bleeding risk: Two case reports.

作者信息

Xu Ning, Li Long-Song, Yue Wen-Yi, Zhao Dan-Qi, Xiang Jing-Yuan, Zhang Bo, Wang Peng-Ju, Cheng Ya-Xuan, Linghu En-Qiang, Chai Ning-Li

机构信息

Senior Department of Gastroenterology, The First Medical Center of PLA General Hospital, Beijing 100853, China.

Department of Radiology, Chinese PLA General Medical School, Beijing 100853, China.

出版信息

World J Gastrointest Surg. 2022 Aug 27;14(8):855-861. doi: 10.4240/wjgs.v14.i8.855.

DOI:10.4240/wjgs.v14.i8.855
PMID:36157367
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9453336/
Abstract

BACKGROUND

Endoscopic ultrasound (EUS)-guided transluminal drainage is an advanced technique used to treat pancreatic fluid collections (PFCs). However, gastric varices and intervening vessels may be associated with a high risk of bleeding and are, therefore, listed as relative contraindications. Herein, we report two patients who underwent interventional embolization before EUS-guided drainage.

CASE SUMMARY

Two 32-year-old males developed symptomatic PFCs after acute pancreatitis and came to our hospital for further treatment. One patient suffered from intermittent abdominal pain and vomiting, and computed tomography (CT) imaging showed an encapsulated cyst 7.93 cm × 6.13 cm in size. The other patient complained of a mass inside the abdomen, which gradually became enlarged. Gastric varices around the ideal puncture site were detected by EUS when we evaluated the possibility of endoscopic drainage in both patients. Interventional embolization was recommended as the first procedure to decrease the risk of bleeding. After that, EUS-guided transluminal drainage was successfully conducted, without vascular rupture. No postoperative complications occurred during hospitalization, and no recurrence was detected at the last follow-up CT scan performed at 1 mo.

CONCLUSION

Interventional embolization is a safe, preoperative procedure that is performed before EUS-guided drainage in PFC patients with gastric varices or at high risk of bleeding.

摘要

背景

内镜超声(EUS)引导下腔内引流是一种用于治疗胰腺液体积聚(PFCs)的先进技术。然而,胃静脉曲张和介入血管可能与高出血风险相关,因此被列为相对禁忌证。在此,我们报告两例在EUS引导下引流前接受介入栓塞治疗的患者。

病例总结

两名32岁男性在急性胰腺炎后出现有症状的PFCs,并前来我院进一步治疗。一名患者出现间歇性腹痛和呕吐,计算机断层扫描(CT)成像显示一个大小为7.93 cm×6.13 cm的包裹性囊肿。另一名患者主诉腹部有肿块,且逐渐增大。在我们评估两名患者的内镜引流可能性时,EUS均检测到理想穿刺部位周围存在胃静脉曲张。建议先行介入栓塞以降低出血风险。之后,成功进行了EUS引导下腔内引流,未发生血管破裂。住院期间未出现术后并发症,在术后1个月进行的最后一次CT随访扫描中未发现复发。

结论

对于存在胃静脉曲张或有高出血风险的PFC患者,介入栓塞是在EUS引导下引流前进行的一种安全的术前操作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/c6cc6c26f3e7/WJGS-14-855-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/d2b9e853d8a6/WJGS-14-855-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/d592f285e785/WJGS-14-855-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/c6cc6c26f3e7/WJGS-14-855-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/d2b9e853d8a6/WJGS-14-855-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/d592f285e785/WJGS-14-855-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/187b/9453336/c6cc6c26f3e7/WJGS-14-855-g003.jpg

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本文引用的文献

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Intern Med. 2022 Mar 15;61(6):771-772. doi: 10.2169/internalmedicine.8159-21. Epub 2021 Aug 31.
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Pancreatic fluid collections: Clinical manifestations, diagnostic evaluation and management.胰腺液体积聚:临床表现、诊断评估和治疗。
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国际多中心综合分析与 lumen-apposing 金属支架放置相关的不良事件用于胰腺液收集引流。
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Management Options for Gastric Variceal Hemorrhage.胃静脉曲张出血的处理方法。
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Percutaneous puncture and embolisation for pancreatitis-related pseudoaneurysm: the feasibility of thrombin injection even in collection of fluid surrounding the pseudoaneurysm.经皮穿刺栓塞治疗胰腺炎相关性假性动脉瘤:即使在假性动脉瘤周围有积液的情况下注射凝血酶的可行性
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