Vorobtsova I E
Radiobiologiia. 1987 May-Jun;27(3):377-81.
The descendants of the first generation of radiation exposed rat males exhibited an increased sensitivity of liver cells to the mutagenic effect of ionizing radiation as was determined by the incidence of chromosome aberrations. It is assumed that the stability of the hereditary apparatus of these animal cells is diminished due to the presence therein of radiation induced injuries of mutation and epigenomic origin at a heterozygous condition.
第一代受辐射雄性大鼠的后代肝细胞对电离辐射的诱变作用表现出更高的敏感性，这是通过染色体畸变发生率确定的。据推测，由于这些动物细胞的遗传装置中存在处于杂合状态的辐射诱导的突变和表观基因组起源的损伤，其遗传稳定性降低。
