Usui Yusuke, Sasada Shinji, Kirita Keisuke, Nagayama Sayaka, Murata Saori, Tsuchiya Yumi, Ishioka Kota, Takahashi Saeko, Nakamura Morio, Kishi Kazuma
Pulmonary Medicine, Tokyo Saiseikai Central Hospital, Tokyo, JPN.
Division of Respiratory Medicine, Department of Internal Medicine, Toho University Graduate School of Medicine, Tokyo, JPN.
Cureus. 2022 Aug 20;14(8):e28197. doi: 10.7759/cureus.28197. eCollection 2022 Aug.
Background As far as we know, there are no reports comparing the safety and cough frequency of transnasal bronchoscopy (TNB) with transoral bronchoscopy (TOB). Methods The subjects were 50 patients who underwent either TNB or TOB and completed the pain score questionnaire between May and November 2020. Complications, pain scores, and cough frequency (times per minute) were compared between the patients with TNB and TOB. A surgical mask was worn over the mouthpiece during the examination. Results Thirty-two and 18 patients underwent TNB and TOB, respectively. Between the two groups, there were no significant differences in examination time and frequency of serious complications. In pain scores, there were no significant differences in terms of anesthesia suffering, several pains during the examination, and availability of re-examination. The TNB group did not feel the prolonged examination time compared to the TOB group (p=0.04). Cough frequency was lower in the TNB group than in the TOB group (0.36 vs 0.73, p=0.027). Moreover, cough frequency in the 25 TNB patients who underwent thin bronchoscopy was significantly lower (0.19 vs 0.73, p<0.01). Conclusions TNB with a surgical mask was well tolerated and safe. Cough frequency in the transnasal thin bronchoscopy was extremely low, suggesting aerosol reduction can be expected.
背景 据我们所知，尚无关于经鼻支气管镜检查（TNB）与经口支气管镜检查（TOB）的安全性和咳嗽频率比较的报告。方法 研究对象为2020年5月至11月期间接受TNB或TOB检查并完成疼痛评分问卷的50例患者。比较TNB组和TOB组患者的并发症、疼痛评分和咳嗽频率（每分钟次数）。检查期间在接口处佩戴外科口罩。结果 分别有32例和18例患者接受了TNB和TOB检查。两组之间，检查时间和严重并发症发生率无显著差异。在疼痛评分方面，麻醉痛苦、检查期间的几次疼痛以及再次检查的可行性方面均无显著差异。与TOB组相比，TNB组未感觉到检查时间延长（p=0.04）。TNB组的咳嗽频率低于TOB组（0.36对0.73，p=0.027）。此外，在接受细支气管镜检查的25例TNB患者中，咳嗽频率显著更低（0.19对0.73，p<0.01）。结论 佩戴外科口罩的TNB耐受性良好且安全。经鼻细支气管镜检查中的咳嗽频率极低，提示有望减少气溶胶产生。
