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催眠改善支气管镜检查的耐受性:BREATH 研究。

Tolerance's improvement of flexible bronchoscopy by Ericksonian hypnosis: The BREATH study.

机构信息

Service de pneumologie, centre hospitalier Robert-Boulin, 112, rue de la Marne, BP 199, 33505 Libourne, France.

出版信息

Respir Med Res. 2022 May;81:100798. doi: 10.1016/j.resmer.2020.100798. Epub 2020 Nov 6.

DOI:10.1016/j.resmer.2020.100798
PMID:35584600
Abstract

AIM

The aim of this study was to determine whether the use of Ericksonian hypnosis may allow an improvement of the tolerance of flexible bronchoscopy.

METHODS

A comparative, two parallel-group, prospective, randomized monocentric clinical trial was conducted. After randomization, patients were divided into two groups: a standard group, in which bronchoscopy was performed according to the official French good practice guidelines and a study group, in which bronchoscopy was performed under hypnosis.

RESULTS

Sixty-seven patients were included, 7 patients were excluded and 60 patients were randomized. No significant differences in age, gender, examination indication and duration were observed between both groups. Two patients of the standard group removed the endoscope by themselves, resulting in a premature termination of bronchoscopy and they were excluded from the statistical analysis. In the standard group, the levels of anxiety, cough, dyspnoea and pain increased during the examination and the addition of local anaesthesia was more often required. In the hypnosis group, levels of anxiety, cough, dyspnoea decreased, whereas only the level of pain increased. There was a statistic significative difference in favour of hypnosis for all the other variables. Moreover, the behaviour score was higher in the standard group: 19.5±14.5 versus 7.3±4.7 (P<0.001), indicating a better tolerance in the hypnosis group. In the standard group, 14 patients refused a new examination under the same conditions versus 7 in the hypnosis group, and 12 patients asked for general anaesthesia in case of a new examination versus 7 in the hypnosis group.

CONCLUSION

This randomised control trial is the first to test the faisability and the potential usefulness of Ericksonian hypnosis during flexible bronchoscopy. Our results indicates an improvement of tolerance and a positive effect on all studied parameters except pain. This method could be widely offered to all patients undergoing flexible bronchoscopy.

摘要

目的

本研究旨在确定是否使用艾瑞克森催眠术可以提高纤维支气管镜检查的耐受性。

方法

进行了一项比较、两平行组、前瞻性、随机单中心临床试验。随机分组后,患者分为两组:标准组,按法国官方良好实践指南进行支气管镜检查;研究组,在催眠下进行支气管镜检查。

结果

共纳入 67 例患者,排除 7 例,随机分为 60 例。两组间年龄、性别、检查指征和检查时间无显著差异。标准组有 2 例患者自行拔出内镜,导致支气管镜检查提前终止,因此被排除在统计分析之外。在标准组,焦虑、咳嗽、呼吸困难和疼痛程度在检查过程中增加,并且需要更多地使用局部麻醉。在催眠组,焦虑、咳嗽和呼吸困难程度降低,而只有疼痛程度增加。所有其他变量都倾向于催眠,存在统计学显著差异。此外,标准组的行为评分更高:19.5±14.5 与 7.3±4.7(P<0.001),表明催眠组的耐受性更好。在标准组,14 例患者拒绝在相同条件下再次接受检查,而催眠组为 7 例;12 例患者要求在新检查时使用全身麻醉,而催眠组为 7 例。

结论

这是第一项测试在纤维支气管镜检查中使用艾瑞克森催眠术的可行性和潜在有用性的随机对照试验。我们的结果表明,耐受性得到改善,对所有研究参数都有积极影响,除了疼痛。这种方法可以广泛提供给所有接受纤维支气管镜检查的患者。

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