Shimizu Hiroshi, Shimizu Masaki, Nakano Toshiya, Noda Kousuke, Tanito Masaki
Department of Ophthalmology, Shimane University Faculty of Medicine, Izumo, Japan.
Meizankai Shimizu Ganka, Matsue, Japan.
Case Rep Ophthalmol. 2022 Jul 14;13(2):556-561. doi: 10.1159/000525797. eCollection 2022 May-Aug.
A 52-year-old man with a history of facioscapulohumeral dystrophy (FSHD) and hypertension presented with decreased vision in his left eye (OS) of several weeks' duration. The best-corrected visual acuity was 1.0 in both eyes (OU), with fundus soft exudates in the right eye (OD) and exudative maculopathy OS. Optical coherence tomography (OCT) showed macular edema and hard exudates OS, and OCT angiography (OCTA) showed nonperfusion areas and arterial tortuosity OU and a capillary aneurysm OS. After photocoagulation of the nonperfusion areas OU and intravitreal injection of aflibercept OS, the macular edema OS decreased and subjective symptoms improved. However, the nonperfusion area OS was enlarged on OCTA. We report the OCTA findings before and after antivascular endothelial growth factor treatment in a patient with FSHD.
一名52岁男性，有面肩肱型肌营养不良症（FSHD）和高血压病史，因左眼（OS）视力下降数周前来就诊。双眼最佳矫正视力均为1.0（OU），右眼（OD）眼底有软性渗出物，左眼有渗出性黄斑病变。光学相干断层扫描（OCT）显示左眼黄斑水肿和硬性渗出物，光学相干断层扫描血管造影（OCTA）显示双眼有非灌注区和动脉迂曲，左眼有毛细血管瘤。对双眼非灌注区进行光凝治疗并左眼玻璃体内注射阿柏西普后，左眼黄斑水肿减轻，主观症状改善。然而，OCTA显示左眼非灌注区扩大。我们报告了一名FSHD患者抗血管内皮生长因子治疗前后的OCTA检查结果。
