Azar Georges, Wolff Benjamin, Cornut Pierre-Loïc, Mauget-Faÿsse Martine
Retinal Department, Rothschild Ophthalmologic Foundation, Paris, France.
Edouard Herriot Hospital, Lyon, France.
GMS Ophthalmol Cases. 2012 Jun 14;2:Doc01. doi: 10.3205/oc000008. eCollection 2012.
To report a case of serous retinal detachment after Pattern Scan Laser (PASCAL) treatment in a diabetic woman.
A 34-year-old diabetic woman presented with florid diabetic retinopathy after a miscarriage during the 20(th) week of pregnancy. Her Best Corrected Visual Acuity (BCVA) was 20/40 right eye (OD) and 20/30 left eye (OS). Fundus exam showed multiple microaneurysms, large blot hemorrhages and venous dilation both eyes (OU). Fundus fluorescein angiography (FFA) revealed large areas of capillary nonperfusion and panretinal neovascularisation in all quadrants OU. Macular Spectral-Domain Optical Coherence Tomography scan (SD-OCT) did not show any foveal thickening. Panretinal photocoagulation (PRP) was immediately performed OU during the same day.
Two days after PASCAL treatment, her BCVA decreased to 20/80 OU and worsened to Count Fingers (CF) during the following days. Fundus exam revealed an extensive serous retinal detachment confirmed on SD-OCT. 2 sub-conjunctival injections of 0.1 ml Betamethasone were done OU. One month later, BCVA improved to 20/30 and SD-OCT confirmed regression of retinal detachment.
PASCAL is considered to be a safe treatment, but one has to be aware of its potential side effects. It has to be used with caution in pregnant women.
报告1例糖尿病女性患者在接受Pattern Scan Laser（PASCAL）治疗后发生浆液性视网膜脱离的病例。
一名34岁的糖尿病女性，在妊娠20周流产后出现严重的糖尿病视网膜病变。她的最佳矫正视力（BCVA）右眼（OD）为20/40，左眼（OS）为20/30。眼底检查显示双眼（OU）均有多个微动脉瘤、大片点状出血和静脉扩张。眼底荧光血管造影（FFA）显示OU象限均有大片无灌注区和全视网膜新生血管形成。黄斑区光谱域光学相干断层扫描（SD-OCT）未显示任何黄斑增厚。同一天立即对OU双眼进行了全视网膜光凝（PRP）。
PASCAL治疗后两天，她的BCVA降至OU 20/80，并在接下来的几天内恶化至指数（CF）。眼底检查发现广泛的浆液性视网膜脱离，SD-OCT证实了这一情况。双眼OU各进行了2次0.1 ml倍他米松结膜下注射。1个月后，BCVA提高到20/30，SD-OCT证实视网膜脱离消退。
PASCAL被认为是一种安全的治疗方法，但必须意识到其潜在的副作用。在孕妇中使用时必须谨慎。
