Jacobs Lucas, Feoli Francesco, Bruderer Pascal, Top Semra, Grozdev Ivan, Cubilier Edouard, Collart Frederic
Nephrology and Dialysis Department, CHU Brugmann, Université Libre de Brussels, Brussels, Belgium.
Dermatopathology and Mycology Unit, CHU Saint Pierre, Université Libre de Brussels, Brussels, Belgium.
Case Rep Nephrol Dial. 2022 Aug 29;12(2):138-144. doi: 10.1159/000524903. eCollection 2022 May-Aug.
Pruritus is highly prevalent in the dialysis population. Its etiology however remains often unclear with uremic pruritus primarily suspected unless compelling evidence of another cause. Although bullous pemphigoid (BP) is considered idiopathic, there are growing data in the literature on BP provoked by different factors, such as medications or surgical procedures. These secondary dermatoses are described as rather mild conditions and more frequent in the elderly Caucasian. We herein describe a newly dialyzed African man of 76 years old, treated by a sulfonylurea such as an antidiabetic drug, who developed a severe BP after jugular catheter placement.
瘙痒症在透析人群中极为普遍。然而,其病因往往仍不明确,除非有其他病因的确凿证据,否则主要怀疑是尿毒症性瘙痒。尽管大疱性类天疱疮(BP)被认为是特发性的,但文献中关于由不同因素(如药物或外科手术)引发的BP的数据越来越多。这些继发性皮肤病被描述为相对较轻的病症,在老年白种人中更为常见。我们在此描述一名76岁新接受透析的非洲男子,他正在使用磺脲类药物作为抗糖尿病药物进行治疗,在置入颈静脉导管后患上了严重的BP。