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一名接受血液透析的患者在颈静脉置管后发生严重大疱性类天疱疮。

Severe Bullous Pemphigoid Onset after Jugular Catheter Placement in a Patient on Hemodialysis.

作者信息

Jacobs Lucas, Feoli Francesco, Bruderer Pascal, Top Semra, Grozdev Ivan, Cubilier Edouard, Collart Frederic

机构信息

Nephrology and Dialysis Department, CHU Brugmann, Université Libre de Brussels, Brussels, Belgium.

Dermatopathology and Mycology Unit, CHU Saint Pierre, Université Libre de Brussels, Brussels, Belgium.

出版信息

Case Rep Nephrol Dial. 2022 Aug 29;12(2):138-144. doi: 10.1159/000524903. eCollection 2022 May-Aug.

DOI:10.1159/000524903
PMID:36160634
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9459599/
Abstract

Pruritus is highly prevalent in the dialysis population. Its etiology however remains often unclear with uremic pruritus primarily suspected unless compelling evidence of another cause. Although bullous pemphigoid (BP) is considered idiopathic, there are growing data in the literature on BP provoked by different factors, such as medications or surgical procedures. These secondary dermatoses are described as rather mild conditions and more frequent in the elderly Caucasian. We herein describe a newly dialyzed African man of 76 years old, treated by a sulfonylurea such as an antidiabetic drug, who developed a severe BP after jugular catheter placement.

摘要

瘙痒症在透析人群中极为普遍。然而,其病因往往仍不明确,除非有其他病因的确凿证据,否则主要怀疑是尿毒症性瘙痒。尽管大疱性类天疱疮(BP)被认为是特发性的,但文献中关于由不同因素(如药物或外科手术)引发的BP的数据越来越多。这些继发性皮肤病被描述为相对较轻的病症,在老年白种人中更为常见。我们在此描述一名76岁新接受透析的非洲男子,他正在使用磺脲类药物作为抗糖尿病药物进行治疗,在置入颈静脉导管后患上了严重的BP。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d45/9459599/45428131be0c/cnd-0012-0138-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d45/9459599/60541413f2ef/cnd-0012-0138-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d45/9459599/45428131be0c/cnd-0012-0138-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d45/9459599/60541413f2ef/cnd-0012-0138-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d45/9459599/45428131be0c/cnd-0012-0138-g02.jpg

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本文引用的文献

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A Case of Localized Bullous Pemphigoid Associated with an Arteriovenous Fistula.1例与动静脉瘘相关的局限性大疱性类天疱疮
Indian J Dermatol. 2020 Nov-Dec;65(6):547-548. doi: 10.4103/ijd.IJD_660_19.
2
Treatment of Bullous Pemphigoid in People Aged 80 Years and Older: A Systematic Review of the Literature.80岁及以上人群大疱性类天疱疮的治疗:文献系统评价
Drugs Aging. 2021 Feb;38(2):125-136. doi: 10.1007/s40266-020-00823-5. Epub 2020 Nov 24.
3
Evaluation of Risk of Bullous Pemphigoid With Initiation of Dipeptidyl Peptidase-4 Inhibitor vs Second-generation Sulfonylurea.
二肽基肽酶-4 抑制剂与第二代磺酰脲类药物起始治疗时大疱性类天疱疮风险评估。
JAMA Dermatol. 2020 Oct 1;156(10):1107-1114. doi: 10.1001/jamadermatol.2020.2158.
4
S2k guidelines for the treatment of pemphigus vulgaris/foliaceus and bullous pemphigoid: 2019 update.寻常型/落叶型天疱疮及大疱性类天疱疮治疗的S2k指南:2019年更新版
J Dtsch Dermatol Ges. 2020 May;18(5):516-526. doi: 10.1111/ddg.14097.
5
Development of Bullous Pemphigoid after Tenckhoff Catheter Placement in a Peritoneal Dialysis Patient.一名腹膜透析患者在置入Tenckhoff导管后发生大疱性类天疱疮
Case Rep Dermatol. 2020 Mar 17;12(1):42-46. doi: 10.1159/000506667. eCollection 2020 Jan-Apr.
6
Dipeptidyl Peptidase-4 Inhibitor-Associated Bullous Pemphigoid.二肽基肽酶-4 抑制剂相关性大疱性类天疱疮。
Front Immunol. 2019 Jun 4;10:1238. doi: 10.3389/fimmu.2019.01238. eCollection 2019.
7
Bullous pemphigoid and diabetes mellitus: Are we missing the larger picture?大疱性类天疱疮与糖尿病:我们是否忽略了更宏观的情况?
J Am Acad Dermatol. 2018 Aug;79(2):e27. doi: 10.1016/j.jaad.2018.02.080.
8
Doxycycline versus prednisolone as an initial treatment strategy for bullous pemphigoid: a pragmatic, non-inferiority, randomised controlled trial.多西环素与泼尼松龙作为天疱疮初始治疗策略的比较:一项实用、非劣效性、随机对照试验。
Lancet. 2017 Apr 22;389(10079):1630-1638. doi: 10.1016/S0140-6736(17)30560-3. Epub 2017 Mar 6.
9
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Int Wound J. 2017 Feb;14(1):288-292. doi: 10.1111/iwj.12670. Epub 2016 Oct 17.
10
Role of physical factors in the pathogenesis of bullous pemphigoid: Case report series and a comprehensive review of the published work.物理因素在大疱性类天疱疮发病机制中的作用:病例报告系列及已发表文献的综合综述
J Dermatol. 2016 Feb;43(2):134-40. doi: 10.1111/1346-8138.13031. Epub 2015 Jul 15.