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继发性牵涉性耳痛的病因及处理方法:一项系统评价与荟萃分析

Aetiology and management options for secondary referred otalgia: a systematic review and meta-analyses.

作者信息

Ally Munira, Moinie Ahmad, Lomas Joan, Borsetto Daniele, Mochloulis George, Bance Manohar, Boscolo-Rizzo Paolo, Vijendren Ananth

机构信息

ENT Department, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, Hertfordshire, UK.

Lister Education Centre, Lister Hospital, East and North Herts NHS Trust, Stevenage, SG1 4AB, UK.

出版信息

Eur Arch Otorhinolaryngol. 2023 Jan;280(1):47-59. doi: 10.1007/s00405-022-07638-7. Epub 2022 Sep 26.

Abstract

OBJECTIVES OF REVIEW

To review the literature for the evidence base for the aetiology and management of referred otalgia, looking particularly at non-malignant, neuralgic, structural and functional issues.

TYPE OF REVIEW

Systematic review.

SEARCH STRATEGY

A systematic literature search was undertaken from the databases of EMBASE, CINAHL, MEDLINE®, BNI, and Cochrane Library according to predefined inclusion and exclusion criteria.

EVALUATION METHOD

All relevant titles, abstracts and full text articles were reviewed by three authors who resolved any differences by discussion and consultation with senior author.

RESULTS

44 articles were included in our review. The overall quality of evidence was low, with the vast majority of the studies being case-series with three cohort and four randomised-controlled trials included. The prime causes and management strategies were focussed on temporomandibular joint dysfunction (TMJD), Eagle syndrome and neuralgia. Our meta-analyses found no difference on the management strategies for the interventions found.

CONCLUSIONS

Referred otalgia is common and treatment should be aimed at the underlying pathology. Potential aetiologies are vast given the extensive sensory innervation of the ear. An understanding of this and a structured approach to patient assessment is important for optimal patient management.

摘要

综述目的

回顾文献,寻找牵涉性耳痛病因及管理的证据基础,尤其关注非恶性、神经痛、结构和功能问题。

综述类型

系统综述。

检索策略

根据预定义的纳入和排除标准,从EMBASE、CINAHL、MEDLINE®、BNI和Cochrane图书馆数据库进行系统文献检索。

评估方法

三位作者对所有相关标题、摘要和全文文章进行评审,通过讨论并咨询资深作者解决任何分歧。

结果

44篇文章纳入我们的综述。证据的总体质量较低,绝大多数研究为病例系列,包括三个队列研究和四个随机对照试验。主要病因和管理策略集中在颞下颌关节功能障碍(TMJD)、伊格尔综合征和神经痛。我们的荟萃分析发现,所发现的干预措施在管理策略上没有差异。

结论

牵涉性耳痛很常见,治疗应针对潜在病理。鉴于耳部广泛的感觉神经支配,潜在病因众多。了解这一点并采用结构化方法进行患者评估对优化患者管理很重要。

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