Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium.
Stroke Unit and Antwerp Neurovascular Center (NVCA), Department of Neurology, Antwerp University Hospital, Antwerp, Belgium.
Acta Neurol Belg. 2023 Apr;123(2):507-512. doi: 10.1007/s13760-022-02085-x. Epub 2022 Sep 27.
Aneurysmal subarachnoid hemorrhages (aSAH) have high mortality and morbidity. However, the impact on Quality of Life (QoL) of patients remains poorly documented, and data on primary caregiver burden is even scarcer.
This is a single center, cross-sectional study performed at the Antwerp University Hospital, Belgium. We included aSAH patients during follow-up at the outpatient clinic and assessed the QoL, by using the Stroke Specific Quality of Life scale (SSQoL). Caregiver burden was evaluated by the Caregiver Strain Index (CSI). The aSAH severity and functional outcome (at 90 days) were assessed, respectively, by mFisher score and modified Ranking Scale (mRS). Statistical analysis was performed using SPSS version 27.
In total, 22 aSAH patients were included, on average 15.5 (range 4-45) months after the aSAH. The SSQoL score was 3.7 ± 0.7, with a mean psychosocial domain score of 3.2 ± 0.8 and physical domain of 4.2 ± 0.8. Psychosocial factors, especially decreased energy levels and cognitive impairment, had a negative impact on the QoL (p = 0.02 en p = 0.05). No association was found between QoL and mFisher, nor between QoL and mRS. Fifteen primary caregivers completed the CSI. Only 3 (20%) of them reported a high care burden (CSI > 6), although changes in daily life and personal plans were reported, respectively, by 73% (n = 11) and 67% (n = 10) of caregivers. We only found a correlation between the mFisher score and CSI (p = 0.01).
Our results emphasize that there is an important psychosocial impact on the QoL of patients after aSAH, and their primary caregivers. More research is warranted.
蛛网膜下腔出血（aSAH）具有高死亡率和高发病率。然而，患者生活质量（QoL）的影响仍记录不佳，关于主要照顾者负担的数据则更为稀缺。
这是一项在比利时安特卫普大学医院进行的单中心横断面研究。我们纳入了在门诊随访期间的 aSAH 患者，并使用中风特定生活质量量表（SSQoL）评估 QoL。通过照顾者压力指数（CSI）评估照顾者负担。aSAH 严重程度和功能结局（90 天后）分别用 mFisher 评分和改良 Ranking 量表（mRS）评估。使用 SPSS 版本 27 进行统计分析。
共纳入 22 例 aSAH 患者，平均在 aSAH 后 15.5（范围 4-45）个月。SSQoL 评分为 3.7±0.7，其中心理社会领域平均评分为 3.2±0.8，生理领域为 4.2±0.8。心理社会因素，尤其是精力下降和认知障碍，对 QoL 有负面影响（p=0.02 和 p=0.05）。QoL 与 mFisher 评分之间以及 QoL 与 mRS 评分之间均无相关性。15 名主要照顾者完成了 CSI。尽管分别有 73%（n=11）和 67%（n=10）的照顾者报告了日常生活和个人计划的变化，但只有 3 名（20%）照顾者报告存在高负担（CSI＞6）。我们仅发现 mFisher 评分与 CSI 之间存在相关性（p=0.01）。
我们的结果强调，aSAH 后患者及其主要照顾者的 QoL 存在重要的心理社会影响。需要进一步研究。
