Suppr超能文献

《急性心力衰竭》:我们是否应该彻底放弃这个术语?

'Acute Heart Failure': Should We Abandon the Term Altogether?

机构信息

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.

Department of Internal Medicine I, University Clinic, RWTH Aachen University, Aachen, Germany.

出版信息

Curr Heart Fail Rep. 2022 Dec;19(6):425-434. doi: 10.1007/s11897-022-00576-9. Epub 2022 Sep 27.

Abstract

PURPOSE OF REVIEW

The distinction between 'acute' and 'chronic' heart failure persists. Our review aims to explore whether reclassifying heart failure decompensation more accurately as an event within the natural history of chronic heart failure has the potential to improve outcomes.

RECENT FINDINGS

Although hospitalisation for worsening heart failure confers a poor prognosis, much of this reflects chronic disease severity. Most patients survive hospitalisation with most deaths occurring in the post-discharge 'vulnerable phase'. Current evidence supports four classes of medications proven to reduce cardiovascular mortality for those who have heart failure with a reduced ejection fraction, with recent trials suggesting worsening heart failure events are opportunities to optimise these therapies. Abandoning the term 'acute heart failure' has the potential to give greater priority to initiating proven pharmacological and device therapies during decompensation episodes, in order to improve outcomes for those who are at the greatest risk.

摘要

目的综述

“急性”和“慢性”心力衰竭之间的区别仍然存在。我们的综述旨在探讨更准确地将心力衰竭失代偿重新分类为慢性心力衰竭自然史中的事件是否有可能改善结局。

最近的发现

尽管因心力衰竭恶化而住院会带来不良预后,但其中大部分反映了慢性疾病的严重程度。大多数患者在出院后的“脆弱阶段”死亡。目前的证据支持四类药物,这些药物已被证明可降低射血分数降低的心力衰竭患者的心血管死亡率,最近的试验表明,心力衰竭恶化事件是优化这些治疗的机会。放弃“急性心力衰竭”这一术语有可能在失代偿发作期间更优先考虑启动已证实的药物和器械治疗,以改善那些风险最高的患者的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6cd/9653344/b68b2b637166/11897_2022_576_Fig1_HTML.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验