Wanitphakdeedecha Rungsima, Yogya Yuri, Yan Chadakan, Phumariyapong Phumithep, Nanchaipruek Yanisorn, Thongjaroensirikul Panwadee, Maneeprasopchoke Pitchaya, Techapichetvanich Thanya, Eimpunth Sasima, Manuskiatti Woraphong
Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Pran-nok Road, Bangkok, 10700, Thailand.
Dermatol Ther (Heidelb). 2022 Nov;12(11):2563-2573. doi: 10.1007/s13555-022-00817-8. Epub 2022 Sep 27.
Monopolar radiofrequency (MRF) is a valuable modality for tightening and contouring mild-to-moderate facial skin laxity. Few studies have evaluated new-generation MRF devices for lower facial laxity in Asians. This study aims to evaluate the efficacy and safety of MRF for treating lower facial laxity in Asians.
This prospective cohort study enrolled 30 volunteers with Fitzpatrick Skin Types III-V and mild-to-moderate skin laxity. Subjects received a single MRF treatment. Self-assessments and adverse events were recorded. Two blinded dermatologists graded improvements (6-point scale) after treatment and 1, 3, and 6 months later.
All subjects completed the study. Treatment energy levels ranged from 2 to 4. The average number of shots was 412 ± 49, delivered in 3-4 passes with 15-30% overlap. All patients reported improvement in lower facial laxity immediately after treatment. Most patients had mild-to-moderate improvement over the 6-month follow-up. Continuous improvement was observed at the 1-, 3-, and 6-month follow-ups (P < 0.01). Significant improvement was seen at the 6-month follow-up compared with the 1-month follow-up (P < 0.01). Subjects tolerated the procedure well: the average pain score was 3.13 out of 10, and no serious adverse events were observed.
The new-generation MRF device we tested was effective and safe for mild-to-moderate lower facial laxity in Asian skin. The latest MRF technology offers improved safety to prevent complications. Appropriate patient selection, setting, and protocols are mandatory to achieve optimal clinical outcomes.
TCTR20210326002.
单极射频（MRF）是改善轻至中度面部皮肤松弛的一种有效方式。很少有研究评估新一代MRF设备对亚洲人下面部松弛的治疗效果。本研究旨在评估MRF治疗亚洲人下面部松弛的有效性和安全性。
这项前瞻性队列研究纳入了30名 Fitzpatrick皮肤分型为III - V型且有轻至中度皮肤松弛的志愿者。受试者接受单次MRF治疗。记录自我评估结果和不良事件。两名皮肤科医生在治疗后以及治疗后1、3和6个月对改善情况进行盲法评分（6分制）。
所有受试者均完成研究。治疗能量水平为2至4。平均发射次数为412 ± 49次，分3 - 4遍进行，重叠率为15 - 30%。所有患者在治疗后即刻均表示下面部松弛情况有所改善。在6个月的随访期内，大多数患者有轻至中度改善。在1、3和6个月的随访中均观察到持续改善（P < 0.01）。与1个月随访相比，6个月随访时改善显著（P < 0.01）。受试者对该治疗耐受性良好：平均疼痛评分为10分制中的3.13分，未观察到严重不良事件。
我们测试的新一代MRF设备对亚洲人轻至中度下面部松弛有效且安全。最新的MRF技术提高了安全性以预防并发症。为实现最佳临床效果，必须进行合适的患者选择、参数设置和治疗方案制定。
TCTR20210326002。
