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冠状动脉旁路移植术后心包后引流及相关因素对晚期心包积液的影响。

Impact of posterior pericardial drain and risk factors on late pericardial effusion after coronary artery bypass surgery.

机构信息

Department of Advanced Biomedical Sciences, Division of Cardiac Surgery, University of Napoli "Federico II" Napoli.

Department of Translational Medical Sciences, University of Napoli 'Federico II', Napoli.

出版信息

J Cardiovasc Med (Hagerstown). 2022 Nov 1;23(11):715-721. doi: 10.2459/JCM.0000000000001370. Epub 2022 Aug 29.

Abstract

BACKGROUND

The blood retained in posterior pericardium can trigger an inflammatory response that increases postoperative atrial fibrillations (POAFs), and it can complicate postoperative course. We retrospectively investigated the impact of a posterior pericardial drain (PPD) in reducing late postoperative pericardial effusion (pPE) and POAFs during the first 30 postoperative days.

METHODS

Two hundred and fifty coronary artery bypass grafting patients were divided into two groups according to the presence of a PPD in addition to the anterior one. Perioperative data and the incidence of POAF were compared. Risk factor analysis was used to determine the predictors of pPE and postpericardiotomy syndrome.

RESULTS

Late pPE was present in 16% of all patients. It proved to be much more frequent in patients with a posterior drain (odds ratio 2.58; 95% confidence interval 1.23-5.79; P  = 0.015) where it seemed to be almost mild and anterior. 'Anterior Drain' patients showed an increased rate of moderate ( P  < 0.001) and posterior effusions ( P  < 0.001). POAF was much more frequent in patients without a PPD (25.2 vs. 6.3%; P  < 0.001). Univariate risk factor analysis revealed a significant association between late pPE and lower preoperative weight ( P  = 0.003), lower preoperative and postoperative serum albumin ( P  < 0.001) and a greater amount of blood transfusion ( P  = 0.02).

CONCLUSION

Even if a PPD is associated with a higher rate of pPE, the patients with only anterior drains were shown to have a greater amount of pericardial effusion and an increased risk of POAFs. Therefore, a PPD should be considered to improve postoperative course.

摘要

背景

心包后残留的血液可引发炎症反应,增加术后心房颤动(POAF)的发生,并使术后病程复杂化。我们回顾性研究了心包后引流(PPD)对减少术后 30 天内心包积液(pPE)和 POAF 的影响。

方法

将 250 例冠状动脉旁路移植术患者根据是否存在心包前引流和心包后引流分为两组。比较围手术期数据和 POAF 的发生率。采用风险因素分析确定 pPE 和心包切开后综合征的预测因素。

结果

所有患者中有 16%出现迟发性 pPE。在后引流组患者中更为常见(优势比 2.58;95%置信区间 1.23-5.79;P=0.015),其中心包后引流组患者的 pPE 似乎为轻度和心包前引流组患者的 pPE 多为中度(P<0.001)和心包后引流组患者的 pPE 多为中度(P<0.001)。无 PPD 患者 POAF 发生率更高(25.2% vs. 6.3%;P<0.001)。单因素风险因素分析显示,迟发性 pPE 与术前体重较低(P=0.003)、术前和术后血清白蛋白较低(P<0.001)以及输血较多(P=0.02)显著相关。

结论

即使心包后引流与更高的 pPE 发生率相关,但仅采用心包前引流的患者心包积液量更大,POAF 风险增加。因此,应考虑使用心包后引流以改善术后病程。

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