严重再生障碍性贫血（AA）中HLA-DPw3频率增加。

Increased frequency of HLA-DPw3 in severe aplastic anemia (AA).

作者信息

Odum N, Platz P, Morling N, Jacobsen N, Jakobsen B K, Ryder L P, Svejgaard A

出版信息

Tissue Antigens. 1987 Apr;29(4):184-5. doi: 10.1111/j.1399-0039.1987.tb01574.x.

DOI:10.1111/j.1399-0039.1987.tb01574.x

Abstract

Thirteen patients with severe aplastic anemia (AA) were HLA-DP typed using primed lymphocyte typing (PLT). The frequency of HLA-DPw3 was significantly increased to 69% in AA as compared to 22% in 160 controls (p less than 0.001; corrected p less than 0.01, RR = 8.0).

摘要

采用预致敏淋巴细胞分型法（PLT）对13例重型再生障碍性贫血（AA）患者进行了HLA - DP分型。与160名对照者中22%的频率相比，AA患者中HLA - DPw3的频率显著增加至69%（p < 0.001；校正p < 0.01，相对危险度RR = 8.0）。