Georgieva D, Todorov B
Vet Med Nauki. 1987;24(1):28-35.
Investigations were carried out with 10 lambs and 4 kids at the age of two months, divided into three groups. The test animals of the first group (5 lambs) were infected with 7,000 T. ovis eggs each, and those of the second group (5 lambs) and those of the third group (4 kids)--with 20,000 T. ovis eggs each. It was found that following infection the total activity of lactate dehydrogenase (LDH) rose, reaching its peak values on the 12th and 15th day. On the 12th day the strongly enhanced enzyme activity was due to the rise of LDH1, while on the 15th day the enhancement was associated with the rise of LDH5 that was characteristic of the skeletal muscles. In the period of forming the connective tissue capsule around the cysticerci the changes in the total activity and the isoenzyme spectrum were more slightly manifested. After the 30th day both the activity and the spectrum of LDH steadily came back to normal. With a C. ovis infection there was also a strongly expressed response on the part of hemopoietic organs, with a pronounced LDH3 activity.
对10只两个月大的羔羊和4只两个月大的山羊羔进行了研究，将它们分成三组。第一组的试验动物（5只羔羊）每只感染7000个绵羊泰勒虫虫卵，第二组（5只羔羊）和第三组（4只山羊羔）每只感染20000个绵羊泰勒虫虫卵。结果发现，感染后乳酸脱氢酶（LDH）的总活性升高，在第12天和第15天达到峰值。在第12天，酶活性的强烈增强是由于LDH1升高所致，而在第15天，增强与骨骼肌特有的LDH5升高有关。在囊尾蚴周围形成结缔组织囊的时期，总活性和同工酶谱的变化表现得较为轻微。30天后，LDH的活性和谱型均稳定恢复正常。感染绵羊住肉孢子虫后，造血器官也有强烈的反应，LDH3活性明显。
