Masalski N, Belchev D, Dimitrov A, Kaloianov I, Kolev V
Vet Med Nauki. 1987;24(2):3-10.
Calves, aged 20 days, were experimentally infected with Salmonella dublin. The animals of one-group were treated at the rate of 6.10(8), and those of another--at 2.10(10) up to 4.10(10) live bacterial cells. The calves of the first group showed no clear clinical symptoms of a disease; neither did they manifest regular shedding of bacterial cells. The calves of the second group presented a typical clinical picture, with more regular shedding of bacteria through nasal discharges and the feces. After killing the animals Salmonella dublin organisms were found in all parenchymal organs and in the lymph nodes. Morphologically, the prevalence was established of inflammatory necrobiotic processes in the liver, with activation and proliferation of the sinus endothelium of the lymph nodes, and catarrhal inflammation of varying manifestation in the small intestine.
20日龄的犊牛被实验性感染都柏林沙门氏菌。一组动物以6×10⁸的剂量进行治疗，另一组动物以2×10¹⁰至4×10¹⁰个活细菌细胞的剂量进行治疗。第一组犊牛未表现出明显的临床疾病症状，也未出现细菌细胞的规律性排出。第二组犊牛呈现出典型的临床症状，通过鼻分泌物和粪便更规律地排出细菌。在处死动物后，在所有实质器官和淋巴结中均发现了都柏林沙门氏菌。在形态学上，确定肝脏中存在炎症性坏死过程，淋巴结窦内皮细胞活化和增殖，小肠出现不同表现的卡他性炎症。
