Sivak J G, Gershon D, Dovrat A, Weerheim J
Vision Res. 1986;26(11):1873-9. doi: 10.1016/0042-6989(86)90139-2.
We describe a technique, involving the projection of low power laser beams through excised lenses in solution, that makes it possible to measure photographically lens optical aberrations. Preliminary work indicates that the laser method can be used in combination with lens culture experiments as a means of monitoring changes in studies of lens biology. The goal of this research is the development of an effective in vitro optical monitor of ocular lenses in order to assist the study of the biochemistry of lens aging and cataractogenesis and be used as a sensitive toxicity measuring device.
我们描述了一种技术,该技术涉及将低功率激光束投射穿过溶液中的离体晶状体,从而能够通过摄影测量晶状体光学像差。初步研究表明,激光方法可与晶状体培养实验相结合,作为监测晶状体生物学研究中变化的一种手段。本研究的目标是开发一种有效的体外晶状体光学监测器,以辅助晶状体老化和白内障形成的生物化学研究,并用作灵敏的毒性测量装置。