Kostava V T, Sharyshev A A, Rakhmaninova A B, Votiakova T V, Evtodienko Iu V
Biofizika. 1979 Mar-Apr;24(2):230-4.
The mechanism of induction of potassium permeability for mitochondrial membranes under special conditions was under study. Conditions were such as: 1--incubation of mitochondria in medium with low meaning of pH (6,0--6,5), 2--incubation in preseace of electrophylic agent--p-(N,N-di-2-chloroethyl) aminophenylacetic acid, which is hydrolized to HCl and 3-lipidsoluble acid, 2,4-dinitrophenol. It is shown that the named mechanism in any case requires the oxidation of lipids of mitochondrial membranes.
正在研究特殊条件下线粒体膜钾通透性诱导机制。这些条件如下：1——线粒体在pH值较低（6.0 - 6.5）的培养基中孵育；2——在亲电试剂——对（N，N - 二 - 2 - 氯乙基）氨基苯乙酸存在下孵育，该试剂水解生成HCl和3 - 脂溶性酸2,4 - 二硝基苯酚。结果表明，无论在何种情况下，上述机制都需要线粒体膜脂质的氧化。
