Karahalios Dean S, Shaw Andrea, Arunga Bonnke, Lenehan Carlee, Sing'oei Valentine, Otieno Walter
SUNY Upstate Medical University Department of Pediatrics, 750 East Adams Street, Syracuse, NY, 13210, USA.
SUNY Upstate Medical University Departments of Medicine, Pediatrics, and International Health, 750 East Adams Street, Syracuse, NY, 13210, USA.
Med Mycol Case Rep. 2022 Sep 16;38:9-12. doi: 10.1016/j.mmcr.2022.09.001. eCollection 2022 Dec.
Subcutaneous phycomycosis becomes a chronic, debilitating condition if left untreated. Treatment includes oral antifungal therapy, though oral potassium iodide has been used in resource-limited settings. Lugol's iodine has been an effective substitute, but little is known about its safety. We report a case of subcutaneous phycomycosis complicated by heart failure during treatment with Lugol's iodine. We review subcutaneous phycomycosis, iodine-mediated cardiotoxicity, as well as social determinants of health relevant to our case, suggesting that Lugol's iodine may only be an effective treatment with proper dosing and long-term monitoring.
如果不进行治疗，皮下藻菌病会发展成一种慢性、使人衰弱的疾病。治疗方法包括口服抗真菌疗法，不过在资源有限的环境中曾使用过口服碘化钾。卢戈氏碘液一直是一种有效的替代品，但对其安全性了解甚少。我们报告了一例在使用卢戈氏碘液治疗期间并发心力衰竭的皮下藻菌病病例。我们回顾了皮下藻菌病、碘介导的心脏毒性以及与我们病例相关的健康社会决定因素，表明卢戈氏碘液可能只有在适当给药和长期监测的情况下才是一种有效的治疗方法。
