Onnis Carlotta, Cadeddu Dessalvi Christian, Cademartiri Filippo, Muscogiuri Giuseppe, Angius Simone, Contini Francesca, Suri Jasjit S, Sironi Sandro, Salgado Rodrigo, Esposito Antonio, Saba Luca
Department of Radiology, Azienda Ospedaliero-Universitaria (A.O.U.), di Cagliari-Polo di Monserrato, Cagliari, Italy.
Department of Medical Sciences and Public Health, Università Degli Studi di Cagliari, Cagliari, Italy.
Front Cardiovasc Med. 2022 Sep 13;9:970438. doi: 10.3389/fcvm.2022.970438. eCollection 2022.
Cardiovascular diseases (CVDs), particularly ischemic heart disease (IHD) and stroke, present epidemiologically in a different way among sexes. The reasons of these sex-based differences should be delved into sex-specific cardiovascular (CV) risk factors and different mechanisms of atherosclerotic progression. Imaging techniques of both carotid and coronary atherosclerotic plaques represent a tool to demonstrate sex-related features which might be used to further and better assess CV risk of male and female population. The aim of this review is to evaluate current knowledge on sex-specific qualitative and quantitative plaque features of coronary and carotid atherosclerosis. We also discuss the clinical implication of a sex-based plaque phenotype, evaluated with non-invasive imaging techniques, such as CT-angiography and MRI-angiography, to stratify CV risk.
心血管疾病（CVDs），尤其是缺血性心脏病（IHD）和中风，在流行病学上存在性别差异。这些基于性别的差异的原因应深入研究性别特异性心血管（CV）危险因素以及动脉粥样硬化进展的不同机制。颈动脉和冠状动脉粥样硬化斑块的成像技术是一种工具，可用于展示与性别相关的特征，这些特征可用于进一步更好地评估男性和女性人群的心血管风险。本综述的目的是评估当前关于冠状动脉和颈动脉粥样硬化性别特异性定性和定量斑块特征的知识。我们还讨论了通过CT血管造影和MRI血管造影等非侵入性成像技术评估的基于性别的斑块表型对心血管风险分层的临床意义。
