Barry Kelly K, Blundell Andrew R, Hawryluk Elena B
Dermatology Section, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Tufts University School of Medicine, Boston, Massachusetts, USA.
Pediatr Dermatol. 2023 Jan;40(1):212-213. doi: 10.1111/pde.15135. Epub 2022 Sep 30.
Cutis verticis gyrata (CVG), characterized by cerebriform overgrowth of the scalp, is rarely observed in congenital melanocytic nevi (CMN). We describe a 13-year-old male with autism and a large CMN of the scalp with numerous satellite nevi whose scalp nevus exhibited evolution with poliosis and CVG. Given the potential association of CVG (independent of CMN) with seizures, neuropsychiatric, and ophthalmologic disorders, and nevus-associated CVG (cerebriform intradermal nevus) with melanoma, multidisciplinary evaluation of CMN patients with CVG is important to guide management and treatment.
头皮回状颅皮(CVG),其特征为头皮呈脑回状过度生长,在先天性黑素细胞痣(CMN)中很少见。我们描述了一名13岁患有自闭症的男性,其头皮有一个巨大的CMN并伴有许多卫星痣,其头皮痣表现为白发症和CVG的演变。鉴于CVG(独立于CMN)与癫痫、神经精神和眼科疾病的潜在关联,以及痣相关的CVG(脑回状皮内痣)与黑色素瘤的关联,对患有CVG的CMN患者进行多学科评估对于指导管理和治疗很重要。