Frosch P J
Z Hautkr. 1987 Jun 15;62(12):919-24.
Topical application of glucocorticoids depends on the type and condition of the dermatosis to be treated. The classification of glucocorticoids into four groups according to their anti-inflammatory potency gives us some orientation for practical reasons. Class I glucocorticoids may be applied to patients with slight atopic dermatitis and are particularly suitable for children. Class II and class III glucocorticoids are indicated for typical dermatoses responding to steroids (eczema of various types, psoriasis, lichen planus, etc.). Class IV glucocorticoids bear a considerable risk of local and systemic side effects and should be restricted to short-term application in severe forms of dermatoses sensitive to glucocorticoids. Diseases associated with deep dermal inflammation (vasculitis, sarcoidosis, keloids) may benefit from this type of glucocorticoids. Glucocorticoids may be saved either by dilution with the vehicle or discontinuous application according to various methods ("tandem" therapy, gradual reduction, intermediate treatment). Further reduction of glucocorticoids may be achieved by extensive application of classic dermatological therapeutics, such as salicylic acid, tar, or anthralin.