Holleboom R G, Bombosch D, Wispels M M H, Giglia G, Tobias T J
Department of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL, Utrecht, The Netherlands.
Department of Biomolecular Health Sciences, Veterinary Pathology Diagnostic Centre, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL, Utrecht, The Netherlands.
Porcine Health Manag. 2022 Sep 30;8(1):40. doi: 10.1186/s40813-022-00285-8.
Cystic hygromas (lymphangiomas) are rarely reported in various animal species, humans included. A hygroma is a benign congenital malformation of the lymphatic drainage system, presenting itself as a mass consisting of multiple cysts of various sizes with a watery content.
This report describes clinical, ultrasonographic, and post-mortem findings of a cystic hygroma in a suckling pig. The mass was characterized by a few thin-walled cysts, containing clear yellow serous fluid. Histologically, the central cavity was lined by a single layer of squamous cells, supported by a thick fibrous stroma. On immunohistochemistry, scattered lining cells were weakly positive for Factor-VIII, suggesting their possible endothelial origin.
This case report contributes to raising awareness on this condition in pigs allowing early identification in life so that appropriate care can be provided. The case report attributes to science on hygromas in general, as better understanding of pathologic features, the aetiology and appropriate treatment are needed.
囊状水瘤(淋巴管瘤)在包括人类在内的各种动物物种中鲜有报道。水瘤是一种淋巴管引流系统的良性先天性畸形,表现为一个由多个大小不一的囊肿组成的肿块,内含水样物质。
本报告描述了一头哺乳仔猪囊状水瘤的临床、超声和尸检结果。该肿块的特征为有几个薄壁囊肿,内含清亮的黄色浆液性液体。组织学上,中央腔由单层鳞状细胞衬里,下方有厚的纤维性间质支持。免疫组化显示,散在的衬里细胞对因子VIII呈弱阳性,提示其可能起源于内皮细胞。
本病例报告有助于提高对猪这种病症的认识,以便在其生命早期进行识别,从而提供适当的护理。该病例报告总体上有助于水瘤相关科学研究,因为需要更好地了解其病理特征、病因及适当的治疗方法。