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皮质骨轨迹螺钉与骨水泥螺钉固定猪脊柱低骨量模型的生物力学分析。

Biomechanical Analysis of Cortical Bone Trajectory Screw Versus Bone Cement Screw for Fixation in Porcine Spinal Low Bone Mass Model.

机构信息

Department of Orthopedics.

Department of Imaging, Tongren Hospital, School of Medicine, Shanghai Jiao Tong University.

出版信息

Clin Spine Surg. 2023 May 1;36(4):E145-E152. doi: 10.1097/BSD.0000000000001395. Epub 2022 Oct 1.

Abstract

STUDY DESIGN

A prospective study of in vitro animal.

OBJECTION

To compare the biomechanics of cortical bone trajectory screw (CBT) and bone cement screw (BC) in an isolated porcine spinal low bone mass model.

SUMMARY OF BACKGROUND DATA

The choice of spinal fixation in patients with osteoporosis remains controversial. Is CBT better than BC? Research on this issue is lacking.

METHODS

Ten porcine spines with 3 segments were treated with EDTA decalcification. After 8 weeks, all the models met the criteria of low bone mass. Ten specimens were randomly divided into groups, group was implanted with CBT screw (CBT group) and the other group was implanted with bone cement screw (BC group). The biomechanical material testing machine was used to compare the porcine spine activities of the two groups in flexion, extension, bending, and axial rotation, and then insertional torque, pull-out force, and anti-compression force of the 2 groups were compared. Independent sample t test was used for comparison between groups.

RESULTS

Ten 3 segments of porcine spine models with low bone mass were established, and the bone mineral density of all models was lower than 0.75 g/cm 2 . There is no difference between the CBT and BC groups in flexion, extension, bending, and axial rotation angle, P >0.05. However, there were significant differences between the 2 groups and the control group, with P <0.01. The 2 groups significantly differed between the insertional torque ( P =0.03) and the screw pull-out force ( P =0.021). The anti-compression forces between the 2 groups have no significant difference between the two groups ( P =0.946).

CONCLUSIONS

The insertional torque and pull-out force of the CBT were higher than those of the BC in the isolated low bone porcine spine model. The range of motion and anti-compression ability of the model was similar between the 2 fixation methods.

摘要

研究设计

体外动物的前瞻性研究。

反对意见

比较皮质骨轨迹螺钉(CBT)和骨水泥螺钉(BC)在孤立的猪脊柱低骨量模型中的生物力学。

背景数据概要

骨质疏松症患者脊柱固定的选择仍存在争议。CBT 比 BC 好吗?关于这个问题的研究还很缺乏。

方法

用 EDTA 脱钙处理 10 个猪脊柱的 3 个节段。8 周后,所有模型均符合低骨量标准。将 10 个标本随机分为两组,一组植入 CBT 螺钉(CBT 组),另一组植入骨水泥螺钉(BC 组)。使用生物力学材料试验机比较两组猪脊柱在屈伸、弯曲和轴向旋转活动的情况,然后比较两组的植入扭矩、拔出力和抗压能力。组间比较采用独立样本 t 检验。

结果

建立了 10 个具有低骨量的 3 节段猪脊柱模型,所有模型的骨密度均低于 0.75 g/cm 2 。CBT 和 BC 组在屈伸、弯曲和轴向旋转角度上无差异,P >0.05。然而,两组与对照组之间存在显著差异,P <0.01。两组之间的植入扭矩(P =0.03)和螺钉拔出力(P =0.021)存在显著差异。两组之间的抗压能力无明显差异(P =0.946)。

结论

在孤立的低骨猪脊柱模型中,CBT 的植入扭矩和拔出力高于 BC。两种固定方法的模型活动范围和抗压能力相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4097/10150626/9e4616fee18f/bsd-36-e145-g001.jpg

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