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CSF neopterin as marker of disease activity in multiple sclerosis.

作者信息

Fredrikson S, Link H, Eneroth P

出版信息

Acta Neurol Scand. 1987 May;75(5):352-5. doi: 10.1111/j.1600-0404.1987.tb05458.x.

DOI:10.1111/j.1600-0404.1987.tb05458.x
PMID:3618112
Abstract

Levels of neopterin, a factor known to be released from macrophages and monocytes at increased rates in cellular immune reactions, were higher in cerebrospinal fluid (CSF) in 10 of 12 patients with multiple sclerosis (MS) during exacerbations in comparison with remissions. This significant elevation in CSF during exacerbations was not reflected in serum. These results indicate that determination of neopterin in CSF may be a useful marker of disease activity in MS.

摘要

相似文献

1
CSF neopterin as marker of disease activity in multiple sclerosis.
Acta Neurol Scand. 1987 May;75(5):352-5. doi: 10.1111/j.1600-0404.1987.tb05458.x.
2
HLA-DR expression and neopterin levels as activity markers in multiple sclerosis.HLA-DR表达和新蝶呤水平作为多发性硬化症的活动标志物
Riv Neurol. 1987 May-Jun;57(3):154-8.
3
Intrathecal production of neopterin in aseptic meningo-encephalitis and multiple sclerosis.无菌性脑膜脑炎和多发性硬化症中鞘内新蝶呤的产生
Clin Exp Immunol. 1987 Jan;67(1):76-81.
4
Studies on activation variables in multiple sclerosis.多发性硬化症中激活变量的研究。
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5
Measurement of immune markers in the serum and cerebrospinal fluid of multiple sclerosis patients during clinical remission.临床缓解期多发性硬化症患者血清和脑脊液中免疫标志物的测量。
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6
[Changes of neopterin in cerebrospinal fluid and serum in children with meningitis].
No To Hattatsu. 1996 Jan;28(1):23-9.
7
Neopterin concentrations in cerebrospinal fluid and serum of individuals infected with HIV-1.感染HIV-1个体的脑脊液和血清中的新蝶呤浓度。
AIDS. 1989 May;3(5):285-8. doi: 10.1097/00002030-198905000-00006.
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Are CSF neopterin levels a marker of disease activity in multiple sclerosis?
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Increased CSF neopterin levels in subarachnoid hemorrhage.蛛网膜下腔出血时脑脊液新蝶呤水平升高。
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10
Interleukin-2, soluble interleukin-2-receptor, neopterin, L-tryptophan and beta 2-microglobulin levels in CSF and serum of patients with relapsing-remitting or chronic-progressive multiple sclerosis.复发缓解型或慢性进展型多发性硬化症患者脑脊液和血清中白细胞介素-2、可溶性白细胞介素-2受体、新蝶呤、L-色氨酸和β2-微球蛋白水平
J Neurol. 1993 Dec;241(2):108-14. doi: 10.1007/BF00869773.

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