宽场无传感器自适应光学扫频源光相干断层血管造影在啮齿动物中的应用。

Wide-field sensorless adaptive optics swept-source optical coherence tomographic angiography in rodents.

出版信息

Opt Lett. 2022 Oct 1;47(19):5060-5063. doi: 10.1364/OL.472387.

Abstract

In this study, we present a sensorless adaptive optics swept-source optical coherence tomographic angiography (sAO-SS-OCTA) imaging system for mice. Real-time graphics processing unit (GPU)-based OCTA image acquisition and processing software were applied to guide wavefront correction using a deformable mirror based on signal strength index (SSI) from both OCT and OCTA images. High-resolution OCTA images with aberrations corrected and contrast enhanced were successfully acquired. Fifty-degree field of view high-resolution montaged OCTA images were also acquired.

摘要

在这项研究中，我们为小鼠展示了一种无传感器自适应光学扫频源光相干断层扫描血管造影（sAO-SS-OCTA）成像系统。实时基于图形处理单元（GPU）的 OCTA 图像采集和处理软件被应用于基于 OCT 和 OCTA 图像的信号强度指数（SSI）引导的波前校正。成功获取了具有像差校正和对比度增强的高分辨率 OCTA 图像。还获取了具有 50 度视场的高分辨率拼接 OCTA 图像。