Department of Plastic and Reconstructive Surgery, Cell & Matrix Research Institute, School of Medicine, Kyungpook National University, Daegu, Korea.
Department of Otolaryngology-Head and Neck Surgery, Lenox Hill and Manhattan Eye, Ear, and Throat Hospitals, Vascular Birthmark Institute of New York, New York Facial Paralysis, New York, USA.
J Oral Pathol Med. 2022 Nov;51(10):872-877. doi: 10.1111/jop.13368. Epub 2022 Nov 22.
Arteriovenous malformations are high-flow congenital vascular malformations that are characterized by abnormal connections between arteries and veins across an abnormal capillary bed. The head and neck region is the most common location for extracranial arteriovenous malformations. Due to their highly invasive, aggressive, and locally destructive nature, arteriovenous malformations are difficult to treat, and management through a multimodal, multidisciplinary approach is recommended. The mainstay of treatment is embolization and surgical excision. With the advent of genetic research, adjuvant targeted medical therapy is starting to play a larger role. Successful surgical treatment with or without embolization requires removal of the nidus. Large, focal, or diffuse lesions involving multiple anatomic areas usually necessitates surgical reconstruction. Free tissue transfer has many advantages over more conservative methods with restoration of function and contour. Herein, the authors describe the surgical treatment and reconstruction in head and neck arteriovenous malformations.
动静脉畸形是一种高流量先天性血管畸形,其特征是动脉和静脉之间穿过异常毛细血管床的异常连接。头颈部是颅外动静脉畸形最常见的部位。由于其具有高度侵袭性、侵袭性和局部破坏性,动静脉畸形难以治疗,建议采用多模式、多学科的方法进行管理。治疗的主要方法是栓塞和手术切除。随着基因研究的出现,辅助靶向药物治疗开始发挥更大的作用。栓塞或不栓塞的成功手术治疗需要切除病灶。涉及多个解剖区域的大型、局灶性或弥漫性病变通常需要手术重建。游离组织移植在功能和轮廓的恢复方面比更保守的方法具有许多优势。在此,作者描述了头颈部动静脉畸形的手术治疗和重建。